Kim Hee Jeong, Park Mi-Hyun, Shin Byungseok
Department of Radiology, Dankook University Hospital, Chungnam, Cheonan-si.
Department of Radiology, Chungnam National University College of Medicine, Daejeon, South Korea.
Medicine (Baltimore). 2018 Dec;97(50):e13616. doi: 10.1097/MD.0000000000013616.
Adenocarcinoma and neuroendocrine tumors are a very rare combination of double primary pancreas tumor.
A Whipple operation was initially performed on a 64-year-old man to remove an adenocarcinoma. Four years after the operation, surveillance- computed tomography revealed abnormal findings of the pancreas. Recurrent adenocarcinoma and neuroendocrine tumor involving different sites of the remnant pancreas were simultaneously detected and characterized on computed tomography and magnetic resonance imaging.
The patient was diagnosed with recurrent adenocarcinoma and neuroendocrine tumor in the post-operative pancreas.
Radical pancreatosplenectomy was performed. The patient underwent subsequent chemotherapy and radiotherapy.
No tumor recurrence was found during the 5 years of follow-up visits.
The possibility of multiple primary tumors of different histological origin should be considered when multiple different pancreatic lesions are detected on images. Computed tomography (CT) and magnetic resonance imaging (MRI) play key roles in the management of multiple tumors in the pancreas.
腺癌和神经内分泌肿瘤是双原发性胰腺肿瘤中非常罕见的组合。
一名64岁男性最初接受了胰十二指肠切除术以切除腺癌。术后四年，监测计算机断层扫描显示胰腺有异常发现。在计算机断层扫描和磁共振成像上同时检测到并确定了累及残余胰腺不同部位的复发性腺癌和神经内分泌肿瘤。
该患者被诊断为术后胰腺复发性腺癌和神经内分泌肿瘤。
进行了根治性胰脾切除术。患者随后接受了化疗和放疗。
在5年的随访中未发现肿瘤复发。
当在影像上检测到多个不同的胰腺病变时，应考虑不同组织学起源的多原发性肿瘤的可能性。计算机断层扫描（CT）和磁共振成像（MRI）在胰腺多肿瘤的管理中起着关键作用。
