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光学相干断层扫描指导下成功治疗一例斑块破裂所致非ST段抬高型心肌梗死患者且未植入支架:病例报告

Optical coherence tomography guided successful treatment without stent implantation in a patient with non-ST-segment elevation myocardial infarction caused by plaque rapture: A case report.

作者信息

Zhang Fei-Fei, Dang Yi, Hao Qing-Qing, Xie Yue-Tao, Li Shu-Ren, Qi Xiao-Yong

机构信息

Department of Cardiology Center, Hebei General Hospital, Shijiazhuang, Hebei Province, China.

出版信息

Medicine (Baltimore). 2018 Dec;97(50):e13669. doi: 10.1097/MD.0000000000013669.

Abstract

RATIONALE

Primary percutaneous coronary intervention (PPCI) with immediate stenting provides effective revascularization. While the risks of no-reflow, stent thrombosis, stent undersizing, and malapposition reduced the benefits in patients with high burden thrombosis. Intravascular imaging, especially optical coherence tomography (OCT), offers potential in optimization of percutaneous coronary intervention.

PATIENT CONCERNS

A 51-year-old male underwent coronary angiography (CAG) due to chest pain with minimal ST-segment depression of the electrocardiogram.

DIAGNOSES

Urgent CAG revealed burden thrombus in the mid left anterior descending coronary artery (LAD) with TIMI grade I distal flow.

INTERVENTIONS

After aspiration thrombectomy, OCT was used to evaluate the target lesion of non-ST-segment elevation myocardial infarction (NSTEMI) and conservative treatment without stent implantation was selected.

OUTCOMES

CAG repeated 1 month after PPCI revealed TIMI grade III blood flow in LAD and only minimal stenosis in the target lesion. OCT showed a cavity formation due to plaque rupture and MLA increased after thrombus dissolution. Follow-up was uneventful at 6 months.

LESSONS

OCT may be useful imaging modality to identify the characteristic of culprit lesion of acute myocardial infarction and subsequently guide individual treatment.

摘要

理论依据

直接支架植入的直接经皮冠状动脉介入治疗(PPCI)可提供有效的血运重建。然而,无复流、支架血栓形成、支架尺寸过小和贴壁不良的风险降低了高负荷血栓患者的获益。血管内成像,尤其是光学相干断层扫描(OCT),在优化经皮冠状动脉介入治疗方面具有潜力。

患者情况

一名51岁男性因胸痛伴心电图ST段轻度压低接受冠状动脉造影(CAG)。

诊断

急诊CAG显示左前降支冠状动脉(LAD)中段有高负荷血栓,TIMI血流分级为I级。

干预措施

在进行血栓抽吸术后,使用OCT评估非ST段抬高型心肌梗死(NSTEMI)的靶病变,并选择了不植入支架的保守治疗。

结果

PPCI术后1个月重复进行CAG显示LAD的TIMI血流分级为III级,靶病变仅存在轻微狭窄。OCT显示由于斑块破裂形成了一个腔隙,血栓溶解后最小管腔面积(MLA)增加。6个月的随访无异常。

经验教训

OCT可能是一种有用的成像方式,可用于识别急性心肌梗死罪犯病变的特征,进而指导个体化治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c74/6320136/09907864a9e4/medi-97-e13669-g001.jpg

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