Colombo F, Casentini L, Zanusso M, Danieli D, Benedetti A
Department of Neurosurgery, City Hospital, Vicenza, Italy.
Acta Neurochir Suppl (Wien). 1988;42:152-6. doi: 10.1007/978-3-7091-8975-7_30.
254 patients affected by intracranial lesions underwent stereotactic biopsy in our department from 1978 to 1986. Target localization was achieved by CT. Multiple biopsy sampling was performed by cup microforceps or sliding cannula. Operative mortality was limited to 2 cases. Definitive tumour diagnosis including type and approximate grading was obtained in 211 (83%) patients. Diagnostic failures have been investigated from the neuroradiological point of view. Failure rate is low in solid tumours with CT homogeneous appearance and clear-cut borders, gradually increases in non homogeneous tumours, necrotic haemorrhagic or cystic, and is high in non classifiable lesions, generally hypodense at CT, with indefinite borders. In the authors opinion the variability of diagnostic retrieval in different types of lesions must be taken into account when proposing stereotactic biopsy.
1978年至1986年期间，我院对254例颅内病变患者进行了立体定向活检。通过CT实现靶点定位。采用杯状微型活检钳或滑动套管进行多次活检采样。手术死亡率仅2例。211例（83%）患者获得了明确的肿瘤诊断，包括肿瘤类型和大致分级。已从神经放射学角度对诊断失败情况进行了研究。CT表现均匀且边界清晰的实性肿瘤诊断失败率较低，在不均匀、坏死出血性或囊性肿瘤中逐渐升高，在无法分类的病变中较高，这些病变在CT上通常呈低密度，边界不明确。作者认为，在提议进行立体定向活检时，必须考虑不同类型病变诊断结果的变异性。
