Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.
Centre for Mental Health, University Health Network, Toronto, Ontario, Canada.
Psychosomatics. 2019 Sep-Oct;60(5):449-457. doi: 10.1016/j.psym.2018.11.007. Epub 2018 Nov 27.
We aimed to describe the rates of psychiatric medication use in bariatric surgery candidates and factors associated with psychiatric medication use.
Patients from the Toronto Western Hospital Bariatric Surgery Program were recruited from 2011 to 2014. Data extracted included demographics, clinical factors (e.g., mood disorder, anxiety disorder, eating disorder, Patient Health Questionnaire-9, Generalized Anxiety Disorder 7), and psychiatric medication use. Logistic regression analyses were used to examine the relationship between demographic variables, clinical factors, and psychiatric medication use. Multiple logistic regression was conducted to determine the predictors of clinical factors from demographic variables with psychiatric medication use.
A total of 262 (35.1%) patients were taking at least 1 psychiatric medication and 105 patients (14.1%) were taking more than 1 psychiatric medication. Antidepressants were the most common psychiatric medication reported. The majority of patients taking a psychiatric medication had a psychiatric illness, with 16.0% not having a lifetime diagnosis of a mental illness. Being male and being employed significantly predicted lower odds of being on a psychiatric medication. Older age significantly predicted higher odds of being on a psychiatric medication. Psychiatric disorders were significantly associated with psychiatric medication use independent of demographic variables.
Our study provides insights into clinical and demographic factors related to psychiatric medication use in bariatric surgery patients. The findings support careful screening and clarification of psychiatric medications, especially in patients without a formal psychiatric diagnosis.
本研究旨在描述肥胖症手术候选者中精神药物的使用情况，并分析其与精神药物使用相关的因素。
研究对象来自于 2011 年至 2014 年多伦多西部医院的肥胖症手术项目。提取的数据包括人口统计学资料、临床因素（如心境障碍、焦虑障碍、饮食障碍、患者健康问卷-9 项、广泛性焦虑障碍 7 项）和精神药物使用情况。采用逻辑回归分析来检验人口统计学变量、临床因素与精神药物使用之间的关系。采用多元逻辑回归分析确定人口统计学变量与精神药物使用相关的临床因素的预测因素。
共有 262 名（35.1%）患者至少使用了一种精神药物，105 名患者（14.1%）使用了超过一种精神药物。报告的最常见精神药物是抗抑郁药。大多数使用精神药物的患者都患有精神疾病，其中 16.0%的患者没有精神疾病的终身诊断。男性和就业状况显著预测了使用精神药物的可能性降低。年龄较大显著预测了使用精神药物的可能性更高。精神障碍与精神药物的使用独立于人口统计学变量显著相关。
本研究提供了肥胖症手术患者中与精神药物使用相关的临床和人口统计学因素的见解。研究结果支持对精神药物进行仔细筛查和澄清，特别是在没有正式精神诊断的患者中。
