Verma Roshan K, Damodharan Niveditha, Angrup Archana, Bakshi Jaimanti, Panda Naresh K
Department of Otolaryngology and Head Neck Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Department of Medical Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.
J Otol. 2018 Jun;13(2):68-74. doi: 10.1016/j.joto.2018.03.001. Epub 2018 Mar 13.
To study the bacteriological profile in a healing mastoid cavity.
This study was a single centre prospective study. Culture swabs from granulations in the mastoid cavity were sent in 40 consecutive patients with squamosal chronic otitis media undergoing mastoidectomy. Cultures were processed for both aerobic and anaerobic bacteria.
Preoperatively: specimens from 26 out of 40 (60.5%) had growth on culture, with 22 (55%) showing only one organism while 4 showing multiple organisms. The commonest organism isolated was pseudomonas (n = 15).At 1 month after mastoidctomy, 11 patients had sterile culture while 29 had growth, of which 26 had aerobic growth and 3 had anaerobic growth. Pseudomonas was seen in 22 patients and staphylococcus in 2 patients. The mean Merchant score was 2.At 3 months: 29 patients (72.5%) had sterile culture from mastoid cavity while 11 patients (27.5%) had growth on culture. All positive cultures were aerobic, including (n = 9) and (n = 2). The mean Merchant score was 1.03. Of the 40 patients, 16 (40%) had a different organism cultured postoperatively compared to preoperative swabs.
Pseudomonas and proteus seem to be the most common organisms responsible for persistent otorrhea after mastoidectomy. Persistent sterile otorrhea was seen in 4 patients (10%) in this group at the end of 3 months. Sterile cultures of preoperative swab are more likely to remain sterile in the postoperative period.
研究愈合中耳乳突腔的细菌学特征。
本研究为单中心前瞻性研究。连续40例接受乳突切除术的鳞状慢性中耳炎患者的乳突腔肉芽组织培养拭子送检。对需氧菌和厌氧菌进行培养。
术前：40例中的26例（60.5%）标本培养有细菌生长，22例（55%）仅显示一种细菌，4例显示多种细菌。分离出的最常见细菌是铜绿假单胞菌（n = 15）。乳突切除术后1个月，11例患者培养无菌生长，29例有细菌生长，其中26例为需氧菌生长，3例为厌氧菌生长。22例患者培养出铜绿假单胞菌，2例培养出葡萄球菌。平均Merchant评分为2分。术后3个月：29例（72.5%）乳突腔培养无菌生长，11例（27.5%）有细菌生长。所有阳性培养均为需氧菌，包括[此处原文缺失具体细菌名称]（n = 9）和[此处原文缺失具体细菌名称]（n = 2）。平均Merchant评分为1.03分。40例患者中，16例（40%）术后培养出的细菌与术前拭子不同。
铜绿假单胞菌和变形杆菌似乎是乳突切除术后持续性耳漏最常见的病原体。该组在3个月末有4例患者（10%）出现持续性无菌性耳漏。术前拭子培养无菌的患者术后更有可能保持无菌。
