Jiang Song, Xie Xiufen
Song Jiang, Department Interventional Treatment, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, Shandong, 250014, China.
Xiufen Xie, Department Interventional Treatment, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, Shandong, 250014, China.
Pak J Med Sci. 2018 Nov-Dec;34(6):1463-1467. doi: 10.12669/pjms.346.15786.
To analyze the clinical effectiveness and safety of early interventional embolization in the treatment of ruptured cerebral aneurysm.
Eighty-eight patients with cerebral aneurysm rupture who were admitted to the hospital between February 2015 and October 2016 were selected as the research subjects and were randomly divided into a control group (N=44) and an observation group (N=44) using random number table. Patients in the control group were given interventional embolization three days after admission, while patients in the observation group were given interventional embolization within three days after admission. The complete, sub complete and incomplete embolization rates were compared between the two groups. The prognosis of the patients was evaluated using modified Rankin scale and modified Barthel index. The incidences of complications were recorded.
The complete, sub-complete and incomplete embolization rates of the observation group and control group were significantly different (P<0.05). The modified Rankin score of the observation group was remarkably lower than that of the control group, and the modified Barthel index of the observation group was remarkably higher than that of the control group; the differences had statistical significance (P<0.05). The incidence of complications of the observation group was lower than that of the control group, and the difference had statistical significance (P<0.05).
Early interventional embolization has satisfactory effect in the treatment of cerebral aneurysm rupture and effectively improve prognosis; hence it is worth promotion in clinical practice.
分析早期介入栓塞治疗破裂脑动脉瘤的临床疗效及安全性。
选取2015年2月至2016年10月收治的88例脑动脉瘤破裂患者作为研究对象，采用随机数字表法将其随机分为对照组（N = 44）和观察组（N = 44）。对照组患者入院3天后给予介入栓塞治疗，观察组患者入院3天内给予介入栓塞治疗。比较两组患者的完全栓塞、次全栓塞及不完全栓塞率。采用改良Rankin量表和改良Barthel指数评估患者预后。记录并发症发生率。
观察组与对照组的完全栓塞、次全栓塞及不完全栓塞率差异有统计学意义（P < 0.05）。观察组改良Rankin评分显著低于对照组，观察组改良Barthel指数显著高于对照组；差异有统计学意义（P < 0.05）。观察组并发症发生率低于对照组，差异有统计学意义（P < 0.05）。
早期介入栓塞治疗破裂脑动脉瘤效果满意，能有效改善预后；值得临床推广应用。
