Arduini D, Rizzo G, Mancuso S, Romanini C
Department of Obstetrics and Gynecology, Universitá Cattolica S. Cuore Roma, Italy.
Am J Obstet Gynecol. 1988 Nov;159(5):1077-80. doi: 10.1016/0002-9378(88)90417-6.
To determine whether maternal oxygen administration affects fetal hemodynamics, we investigated 10 healthy fetuses and 10 growth-retarded fetuses near term by means of Doppler ultrasonography. The growth-retarded fetuses were characterized by abnormal blood flow velocity waveforms. Velocity waveforms were simultaneously recorded at 5-minute intervals from the fetal descending aorta and internal carotid artery before, during, and after maternal oxygen administered through a face mask that delivered 60% oxygen. The pulsatility index was calculated. During oxygen treatment growth-retarded fetuses showed significant temporary hemodynamic modifications as expressed by changes of pulsatility index values that increased in the internal carotid artery and decreased at the level of the descending aorta. On the other side no changes were found in healthy fetuses. These findings suggest that maternal oxygen administration can modify fetal hemodynamics in cases of growth retardation associated with abnormal blood flow velocity waveforms.
为了确定母体吸氧是否会影响胎儿血流动力学，我们通过多普勒超声检查对10例足月健康胎儿和10例生长受限胎儿进行了研究。生长受限胎儿的特征是血流速度波形异常。在通过输送60%氧气的面罩给予母体吸氧之前、期间和之后，每隔5分钟同时记录胎儿降主动脉和颈内动脉的速度波形。计算搏动指数。在吸氧治疗期间，生长受限胎儿表现出明显的暂时性血流动力学改变，表现为搏动指数值的变化，颈内动脉搏动指数值增加，降主动脉水平搏动指数值降低。另一方面，健康胎儿未发现变化。这些发现表明，在伴有血流速度波形异常的生长受限病例中，母体吸氧可改变胎儿血流动力学。
