[Nitrogen metabolism of Streptomyces antibioticus on media with various glucose contents].

The dynamics of the glutamine synthetase and glutamate dehydrogenase activity was studied during cultivation of Str. antibioticus on media with different contents of glucose and ammonium sulfate. No correlation between the enzymes activity and the levels of oleandomycin production by the mycelium was observed. It was shown that the levels of oleandomycin biosynthesis repression by glucose did not depend on ammonium sulfate concentration in the medium.