胃食管反流病中的牙齿侵蚀。一项系统评价。
Dental erosion in gastro-esophageal reflux disease. A systematic review.
作者信息
Picos Andrei, Badea Mândra Eugenia, Dumitrascu Dan Lucian
机构信息
Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
出版信息
Clujul Med. 2018 Oct;91(4):387-390. doi: 10.15386/cjmed-1017. Epub 2018 Oct 30.
UNLABELLED
The growing interest reflected in the studies on dental erosion is justified by the severe health problems it entails, i.e. esthetic, phonetic, masticatory disturbances and pulp complications. Most studies investigate the prevalence of dental erosion in adults and children, the severity of lesions and etiopathogenetic factors.
BACKGROUND AND AIM
Dental erosions (DE) are one of the extraesophageal complications of gastroesophageal reflux disease (GERD). An increasing amount of papers shed light on this topic. We carried out a systematic review on the association between GERD and DE.
METHODS
We studied the association between DE and GERD in adults and children. The search for published studies was performed in PubMed using search terms "dental erosion" and "gastro-esophageal reflux disease". References published since 2007 were included and a systematic review was carried out. Articles not assessing DE in GERD patients were excluded, and also case presentations and articles in languages of limited circulation. The prevalence of DE in patients with GERD, extrinsic and intrinsic etiological factors of DE and the severity of dental erosion lesions were analyzed.
RESULTS
A total of 273 articles were found, 10 studies being retained for analysis. Correlations between DE and GERD, namely the prevalence and severity of dental erosion in GERD patients, were investigated. DE prevalence was between 10.6% - 42%, median 25.5%. Mean values of DE prevalence were 48.81% in GERD patients, compared to 20.48% in non-GERD controls. Comparative values of DE frequency in adults with GERD was 38.96%, compared to 98.1% in children with GERD.
CONCLUSIONS
DE is a condition associated with GERD. DE prevalence is higher in GERD patients. Intrinsic pathogenetic factors with direct action on the hard dental tissues are GERD, while extrinsic factors are represented by diet. Among the patients diagnosed with GERD, youth under the age of 18 had a higher frequency compared to adults.
未标注
关于牙侵蚀的研究中日益增长的兴趣是合理的，因为它会引发严重的健康问题，即美学、语音、咀嚼功能障碍和牙髓并发症。大多数研究调查了成人和儿童牙侵蚀的患病率、病变严重程度和病因学因素。
背景与目的
牙侵蚀（DE）是胃食管反流病（GERD）的食管外并发症之一。越来越多的论文阐明了这一主题。我们对GERD与DE之间的关联进行了系统综述。
方法
我们研究了成人和儿童中DE与GERD之间的关联。在PubMed中使用搜索词“牙侵蚀”和“胃食管反流病”对已发表的研究进行搜索。纳入2007年以来发表的参考文献并进行系统综述。排除未评估GERD患者中DE的文章，以及病例报告和流通量有限语言的文章。分析了GERD患者中DE的患病率、DE的外在和内在病因以及牙侵蚀病变的严重程度。
结果
共找到273篇文章，保留10项研究进行分析。研究了DE与GERD之间的相关性，即GERD患者中牙侵蚀的患病率和严重程度。DE患病率在10.6% - 42%之间，中位数为25.5%。GERD患者中DE患病率的平均值为48.81%，而非GERD对照组为20.48%。GERD成人患者中DE频率的比较值为38.96%，而GERD儿童患者为98.1%。
结论
DE是一种与GERD相关的病症。GERD患者中DE患病率更高。对硬牙组织有直接作用的内在致病因素是GERD，而外在因素以饮食为代表。在诊断为GERD的患者中，18岁以下的年轻人比成年人的频率更高。
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