Asarkar Ameya, Takalkar Amol, Dhawan Manish, Nathan Cherie Ann O
Department of Otolaryngology/HNS, Louisiana State University Health Sciences Center Shreveport, Shreveport, Louisiana, USA.
Center for Molecular Imaging and Therapy, Biomedical Research Foundation of Northwest Louisiana, Shreveport, Louisiana, USA.
BMJ Case Rep. 2018 Dec 3;11(1):bcr2018226636. doi: 10.1136/bcr-2018-226636.
Salivary duct carcinoma (SDC) is a rare and extremely aggressive salivary gland cancer. An 81-year-old woman with SDC underwent a total parotidectomy with facial nerve sacrifice and a neck dissection. Following surgery, she was diagnosed with disseminated bone marrow metastases. She underwent chemotherapy and trastuzumab for palliation. We present a case of SDC of the parotid which was diagnosed with disseminated bone marrow metastasis following surgery for the primary. This case also highlights the importance of having a high index of suspicion while evaluating highly aggressive tumours like SDC for any atypical findings during workup.
涎腺导管癌(SDC)是一种罕见且侵袭性极强的涎腺癌。一名81岁患有涎腺导管癌的女性接受了牺牲面神经的全腮腺切除术及颈部淋巴结清扫术。术后,她被诊断为骨髓弥漫性转移。她接受了化疗和曲妥珠单抗治疗以缓解症状。我们报告一例腮腺涎腺导管癌病例,该病例在原发性肿瘤手术后被诊断为骨髓弥漫性转移。该病例还凸显了在评估像涎腺导管癌这样的高度侵袭性肿瘤时,在检查过程中对任何非典型发现保持高度怀疑的重要性。