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定量分析在子宫内膜癌中的预后价值。

The prognostic value of quantitative analysis in the endometrial carcinoma.

作者信息

Aalto M L

机构信息

Department of Pathology, University of Kuopio, Finland.

出版信息

Eur J Obstet Gynecol Reprod Biol. 1988 Oct;29(2):159-65. doi: 10.1016/0028-2243(88)90143-8.

DOI:10.1016/0028-2243(88)90143-8
PMID:3056754
Abstract

The epithelial and stromal components in 146 adenocarcinomas, adenocanthomas and adenosquamous carcinomas of the endometrium were quantified morphometrically on Feulgen-stained tissue sections. The classification of the tumors was based on the criteria of World Health Organization and International Federation of Gynecology and Obstetrics. As expected, the survival percentage of the patients fell with the advancing clinical stage and histological grade. The ratio of the epithelial cells to the stromal ones proved to be a good prognostic indicator and may be useful in identification of cases with the most favorable prognosis among grade 1 tumors. A high mitotic activity predicted poor prognosis to the patient although statistical significance was not achieved.

摘要

对146例子宫内膜腺癌、腺棘皮癌和腺鳞癌的福尔根染色组织切片进行形态计量学分析,以定量上皮和间质成分。肿瘤分类依据世界卫生组织及国际妇产科联盟的标准。正如预期,患者的生存率随临床分期和组织学分级的进展而下降。上皮细胞与间质细胞的比例被证明是一个良好的预后指标,可能有助于识别1级肿瘤中预后最良好的病例。有丝分裂活性高预示患者预后不良,尽管未达到统计学意义。

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