Gainder Shalini, Arora Parul, Dhaliwal Lakhbir Kaur
Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
J Hum Reprod Sci. 2018 Jul-Sep;11(3):286-290. doi: 10.4103/jhrs.JHRS_33_18.
Midtrimester surgical abortions often result in retained intrauterine fetal bones and consequent secondary infertility.
To study the incidence of women presenting with retained intrauterine bones as a cause of secondary infertility in a tertiary level Indian hospital and pregnancy rates following retrieval of these fragments.
Retrospective data analysis in the infertility clinic of PGIMER (Post Graduate Institute of Medical Education and Research), a tertiary level hospital of Northern India.
Women diagnosed with retained intrauterine bony fragments were subjected to hysteroscopic removal of these fragments. Incidentally diagnosed retained bones on hysteroscopy were also removed. Such women were followed for spontaneous resumption of fertility or were subjected to ovulation induction, and pregnancy rates were noted.
Retained fetal bones accounted for 0.28% of all women with infertility and 12% (22/144) of all the uterine causes of infertility requiring an operative hysteroscopic procedure for treatment. Only 5 (27.7%) of 18 women conceived after the hysteroscopic retrieval of bony fragments: three had full-term vaginal deliveries, one had a midtrimester abortion, and one woman is in her third trimester.
Despite surgical retrieval, fertility rates may be lower due to inflammatory damage to the endometrium.
孕中期手术流产常导致宫内胎儿骨骼残留,进而引发继发性不孕。
研究在印度一家三级医院中,因宫内骨骼残留导致继发性不孕的女性发生率,以及取出这些碎片后的妊娠率。
在印度北部一家三级医院PGIMER(医学教育与研究研究生学院)的不孕不育诊所进行回顾性数据分析。
诊断为宫内骨碎片残留的女性接受宫腔镜下这些碎片的取出术。宫腔镜检查时偶然发现的残留骨骼也予以取出。对这些女性进行随访,观察其生育能力是否自然恢复,或进行促排卵治疗,并记录妊娠率。
残留胎儿骨骼在所有不孕女性中占0.28%,在所有需要宫腔镜手术治疗的子宫性不孕原因中占12%(22/144)。18名女性在宫腔镜取出骨碎片后,仅有5名(27.7%)受孕:3名足月阴道分娩,1名孕中期流产,1名女性处于孕晚期。
尽管进行了手术取出,但由于子宫内膜的炎性损伤,生育率可能较低。