Singh Mitasha, Pal Ranabir, Yarasani Pradeep, Bhandarkar Prashant, Munivenkatappa Ashok, Agrawal Amit
Department of Community Medicine, ESIC Medical College and Hospital, Faridabad, Haryana, India.
Department of Community Medicine, MGM Medical College and Hospital, Kishanganj, Bihar, India.
J Emerg Trauma Shock. 2018 Oct-Dec;11(4):253-264. doi: 10.4103/JETS.JETS_90_17.
Traumatic brain injury (TBI) is the leading cause of mortality, morbidity, and disability globally. Methods for a reliable prediction of outcomes on the admission of TBI cases are of great clinical relevance to stakeholders.
This study used the International Classification of Diseases-10 codes (S00-S09) for analysis of injury distribution of TBI patients and attempted to find the prognostic predictors of Glasgow coma scale (GCS) in the outcome from readily accessible parameters.
The data were reanalyzed from the Towards Improved Trauma Care Outcomes (TITCO) project from India. TITCO is the prospective, observational, multicenter trauma registry, contained data of trauma patients admitted to four public university hospitals in Mumbai, Delhi, and Kolkata collected from October 2013 to September 2015.
Among 8525 cases under study, low GCS scores before admission, which was dependent on the demographic variables and related risk factors occurring at the time of injury, were important in the prognostic predictors of mortality. However, survival probability during hospitalization remained uniformly uncertain for the elderly. Death as outcome of injury was dependent on the average intensity of injury, GCS on admission, critical injury severity score, and intubation within 1 h of admission and between 1 and 24 h of admission. These factors emerged as the independent predictors of fatality. The time of the day of injury did not yield any significant association with low GCS or demise in our study.
GCS <8, i.e., severe at the time of admission, was an unfavorable predictor of in-hospital mortality.
创伤性脑损伤(TBI)是全球范围内导致死亡、发病和残疾的主要原因。在TBI病例入院时进行可靠预后预测的方法对利益相关者具有重大临床意义。
本研究使用国际疾病分类第10版编码(S00-S09)分析TBI患者的损伤分布,并试图从易于获取的参数中找出格拉斯哥昏迷量表(GCS)在预后中的预测因素。
对来自印度的改善创伤护理结果(TITCO)项目的数据进行重新分析。TITCO是一项前瞻性、观察性、多中心创伤登记研究,包含2013年10月至2015年9月期间在孟买、德里和加尔各答的四家公立大学医院收治的创伤患者的数据。
在8525例研究病例中,入院前低GCS评分取决于人口统计学变量和受伤时出现的相关危险因素,是死亡率预后预测的重要因素。然而,老年人住院期间的生存概率仍然普遍不确定。损伤导致的死亡取决于损伤的平均强度、入院时的GCS、严重损伤严重程度评分以及入院后1小时内和1至24小时内的插管情况。这些因素成为死亡的独立预测因素。在我们的研究中,受伤时间与低GCS或死亡没有显著关联。
GCS<8,即入院时为重度,是院内死亡率的不利预测因素。