Suda Masayo, Nakanishi Hideo, Akagi Tadamichi, Murakami Tomoaki, Suzuma Kiyoshi, Suda Kenji, Kameda Takanori, Morooka Satoshi, Ikeda Hanako Ohashi, Tsujikawa Akitaka
Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan,
Clin Ophthalmol. 2018 Nov 28;12:2439-2449. doi: 10.2147/OPTH.S183689. eCollection 2018.
To describe the 1-year surgical outcomes of both Baerveldt glaucoma implant (BGI) and the Ahmed glaucoma valve (AGV) implant with pars plana tube insertion in Japanese eyes with neovascular glaucoma (NVG).
This was a retrospective study of 21 eyes of 18 patients who had undergone BGI (10 eyes) or AGV (11 eyes) implantation. The 1-year surgical outcomes in the two groups were compared. Surgical success was defined as an intraocular pressure (IOP) of 6-21 mmHg (criterion A) or 6-18 mmHg (criterion B) with >20% reduction regardless of the use of antiglaucoma medications.
The mean preoperative IOP was 33.9±6.6 mmHg in the BGI group and 30.9±5.3 mmHg in the AGV group (=0.31). The IOP at 1-year was lower in the BGI group at 10.3±5.9 mmHg than in the AGV group at 14.8±3.3 mmHg (=0.044). The mean number of glaucoma medications at 1 year was 1.0±1.3 in the BGI group and 1.4±1.4 in the AGV group (=0.57). The incidence of postoperative complications during the 1-year follow-up was not statistically different between the two groups; however, one eye in the BGI group lost light perception after additional surgery for Hoffman elbow exposure. The 1-year success rates of the BGI group was 60.0% and that in the AGV group was 90.9% based on criterion A (=0.095), and 50.0% and 81.8% based on criterion B (=0.074).
Significant reductions of the IOP and number of glaucoma medications were achieved at 1 year after both types of implants in Japanese eyes with NVG.
描述在日本新生血管性青光眼（NVG）患者眼中，经平坦部植入Baerveldt青光眼引流物（BGI）和Ahmed青光眼阀门（AGV）植入物的1年手术效果。
这是一项对18例患者的21只眼睛进行的回顾性研究，这些患者接受了BGI植入（10只眼）或AGV植入（11只眼）。比较两组的1年手术效果。手术成功定义为眼压（IOP）在6 - 21 mmHg（标准A）或6 - 18 mmHg（标准B），无论是否使用抗青光眼药物，眼压降低>20%。
BGI组术前平均眼压为33.9±6.6 mmHg，AGV组为30.9±5.3 mmHg（P = 0.31）。1年时BGI组眼压为10.3±5.9 mmHg，低于AGV组的14.8±3.3 mmHg（P = 0.044）。1年时BGI组青光眼药物平均使用数量为1.0±1.3，AGV组为1.4±1.4（P = 0.57）。两组在1年随访期间术后并发症发生率无统计学差异；然而，BGI组有1只眼在因霍夫曼肘关节暴露进行额外手术后失去光感。基于标准A，BGI组1年成功率为60.0%，AGV组为90.9%（P = 0.095）；基于标准B，分别为50.0%和81.8%（P = 0.074）。
在日本NVG患者眼中，两种植入物植入1年后眼压和青光眼药物使用数量均显著降低。
