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[口服N-苯甲酰-L-酪氨酰-对氨基苯甲酸(PFT)在评估胰腺外分泌功能中的应用及其在胰腺疾病诊断方法中的价值(作者译)]

[The oral administration of N-benzoyl-L-tyrosyl-paraaminobenzoic acid (PFT) in the assessment of exocrine pancreatic function and its value within the diagnostic approach to pancreatic disease (author's transl)].

作者信息

Fettes F, Gyr K, Singeisen M, Kayasseh L, Stalder G A

出版信息

Z Gastroenterol. 1978 Mar;16(3):141-8.

PMID:305693
Abstract

Exocrine pancreatic function was determined by the oral administration of N-benzoyl-L-tyrosyl-PABA in 343 persons, including controls, patients with diseases of the pancreas, and patients with non-pancreatic disease. The results revealed a sensitivity of 85% in chronic pancreatitis and of 78% in carcinoma of the pancreas. The specificity of the PFT amounted to 92%. No toxic side effects were noted. The PFT is likely to be a useful screening procedure for pancreatic disease.

摘要

通过口服N-苯甲酰-L-酪氨酰对氨基苯甲酸(N-benzoyl-L-tyrosyl-PABA)测定了343人的外分泌胰腺功能,其中包括对照组、胰腺疾病患者和非胰腺疾病患者。结果显示,该方法对慢性胰腺炎的敏感度为85%,对胰腺癌的敏感度为78%。胰腺功能试验(PFT)的特异性为92%。未观察到毒性副作用。PFT可能是一种用于筛查胰腺疾病的有用方法。

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