Kostić N, Bozanić M, Vuković A
Ward of Gastroenterology, Dr. Dragisa Misović Clinical Hospital Centre, Belgrade.
Srp Arh Celok Lek. 1992 Sep-Oct;120(9-10):269-72.
N benzoyl-L-tyrosil PABA was orally administered to 13 controls and 35 patients with pancreatic disease: 7 with chronic exocrine pancreatic disease, 7 patients after an attack of acute pancreatitis, 3 with carcinoma of the pancreas, 8 with biliary tract disease and 10 with diabetes. The amount of PABA excreted serves as parameter exocrine pancreatic function. PABA excretion in patients with chronic pancreatitis (p < 0.01) and diabetes (p < 0.05) was significantly less then in controls. The present data justify further investigation of this procedure as a possible new oral test of exocrine pancreatic function.
将N-苯甲酰-L-酪氨酸对氨基苯甲酸口服给予13名对照者和35名胰腺疾病患者:7名慢性外分泌性胰腺疾病患者、7名急性胰腺炎发作后的患者、3名胰腺癌患者、8名胆道疾病患者和10名糖尿病患者。对氨基苯甲酸的排泄量作为外分泌胰腺功能的参数。慢性胰腺炎患者(p<0.01)和糖尿病患者(p<0.05)的对氨基苯甲酸排泄量显著低于对照者。目前的数据证明有必要进一步研究该方法,将其作为一种可能的外分泌胰腺功能新的口服检测方法。