Diamond Gary, Hagemeyer Alfred, Murphy Vince, Sokolovskii Valery
Rennovia, Inc., 3040 Oakmead Village Drive, Santa Clara, CA 95051, United States.
Alva Consulting, 320 Logue Ave., Mountain View, CA 94043, United States.
Comb Chem High Throughput Screen. 2018;21(9):616-630. doi: 10.2174/1386207322666181219155050.
The transformation of low cost sugar feedstocks into market chemicals and monomers for existing or novel high performance polymers by chemical catalysis is reviewed. Emphasis is given to industrially relevant, continuous flow, trickle bed processes. Since long-term catalyst stability under hydrothermal conditions is an important issue to be addressed in liquid phase catalysis using carbohydrate feedstocks, we will primarily discuss the results of catalytic performance for prolonged times on stream. In particular, the selective aerobic oxidation of glucose to glucaric acid and the subsequent selective hydrogenation to adipic acid is reviewed. Hydroxymethylfurfural (HMF), which is readily available from fructose, can be upgraded by oxidation to furan dicarboxylic acid (FDCA) or by consecutive reduction and hydrogenolysis to hexanetriol (HTO) followed by hydrogenolysis to biobased hexanediol (HDO). Direct amination of HDO yields biobased hexamethylene diamine (HMDA). Aerobic oxidation of HDO represents an alternative route to biobased adipic acid. HMDA and adipic acid are the monomers required for the production of nylon- 6,6, a major polymer for engineering and fibre applications.
本文综述了通过化学催化将低成本糖原料转化为现有或新型高性能聚合物的市场化学品和单体的过程。重点介绍了与工业相关的连续流滴流床工艺。由于在使用碳水化合物原料的液相催化中，水热条件下催化剂的长期稳定性是一个需要解决的重要问题，因此我们将主要讨论长时间运行的催化性能结果。特别地，本文综述了葡萄糖选择性好氧氧化制葡萄糖二酸以及随后选择性加氢制己二酸的过程。由果糖可容易制得的羟甲基糠醛（HMF），可通过氧化升级为呋喃二甲酸（FDCA），或通过连续还原和氢解为己三醇（HTO），随后氢解为生物基己二醇（HDO）。HDO的直接胺化可得到生物基己二胺（HMDA）。HDO的好氧氧化是生产生物基己二酸的另一条途径。HMDA和己二酸是生产尼龙6,6所需的单体，尼龙6,6是一种主要用于工程和纤维应用的聚合物。
