Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, U.S.A.
Laryngoscope. 2019 Sep;129(9):2071-2075. doi: 10.1002/lary.27632. Epub 2018 Dec 20.
OBJECTIVES/HYPOTHESIS: To describe a previously unreported variant of Frey syndrome. Gustatory sweating is a common complication of parotidectomy and typically directly overlies the surgical site or parotid bed. In some instances, the sweating may occur beyond the parotid bed or involve tissue that was undisturbed during the procedure.
Retrospective case series.
All cases of temporoparietal Frey syndrome in a single surgeon's experience were reviewed.
Seven patients were found to have temporoparietal Frey syndrome. Three patients had concomitant first bite syndrome. Three patients had some form of reconstruction at time of surgery. The mean time to onset of symptoms was 11.5 months, with a range of 7 to 21 months. Four patients did not require any treatment for their symptoms, but two patients required intradermal Botox injections for symptomatic relief.
This study describes a previously unreported variant of Frey syndrome with symptoms occurring distal to the parotid gland. This likely develops either by regeneration of severed postganglionic fibers into sympathetic targets distally along the course of the auriculotemporal nerve or by regeneration into fibers of the sympathetic plexus traveling along the superficial temporal artery.
Laryngoscope, 129:2071-2075, 2019.
目的/假设：描述一种以前未报道的 Frey 综合征变异。味觉性出汗是腮腺切除术的常见并发症，通常直接位于手术部位或腮腺床上方。在某些情况下，出汗可能发生在腮腺床之外或涉及手术过程中未受干扰的组织。
回顾性病例系列。
回顾了一位外科医生经验中的所有颞浅部 Frey 综合征病例。
发现 7 例颞浅部 Frey 综合征患者。3 例伴有第一咬综合征。3 例患者在手术时进行了某种形式的重建。症状出现的平均时间为 11.5 个月，范围为 7 至 21 个月。4 例患者的症状无需治疗，但 2 例患者需要皮内注射肉毒杆菌毒素以缓解症状。
本研究描述了一种以前未报道的 Frey 综合征变异，其症状发生在腮腺远端。这可能是通过切断的节后纤维沿着耳颞神经的走行再生到交感神经靶位，或者通过沿着颞浅动脉走行的交感神经丛纤维再生而发生的。
喉镜，129：2071-2075，2019。
