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腮腺良性肿瘤切除术后Frey综合征典型和非典型症状的晚期患病率

Late Prevalence of Typical and Atypical Symptoms of Frey's Syndrome after Parotidectomy for Benign Tumor.

作者信息

Marchese Maria Raffaella, Rossi Federica, Settimi Stefano, Galli Jacopo

机构信息

Otolaryngology Division, Department of Neurosciences, Sensory Organs and Thorax, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, 00168 Rome, Italy.

Section of Otolaryngology, Head-Neck and Sense Organs Department, Catholic University of the Sacred Heart, 00168 Rome, Italy.

出版信息

J Pers Med. 2024 Jan 16;14(1):96. doi: 10.3390/jpm14010096.

DOI:10.3390/jpm14010096
PMID:38248797
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10820002/
Abstract

BACKGROUND

The treatment of choice for tumors located in the parotid gland is surgery. Nevertheless, postoperative complications are not infrequent. Regardless of the type of surgical procedure, the most common complication is Frey's syndrome (FS). Traditionally, FS includes unilateral gustatory sweating and flushing of the facial skin lining the parotid compartment. Recent research describes atypical discomfort associated with FS. The aim of this study was to assess the late prevalence and severity of both usual and atypical symptoms after parotidectomy for benign tumors.

METHODS

We conducted a cross-sectional study involving 86 subjects who underwent superficial parotidectomy at least one year before the study. The questionnaire included the sweating-flushing-itch-paresthesia-pain (SFIPP) Frey scale supplemented by specific questions about symptoms.

RESULTS

Sixty-seven out of eighty-six (77.9%) cases reported almost one symptom. The most frequent symptom was itch (36/67-53.7%), followed by pain (35/67-52.2%), while 28/67 (41.8%) subjects complained of atypical symptoms without flushing or sweating. A desire to treat the discomfort was reported by 50/67 (74.6%) subjects.

CONCLUSIONS

Late postparotidectomy local discomfort is not infrequent and includes both usual and "unusual" symptoms almost equally. Our results suggest the importance of informing patients about the occurrence of the syndrome and the available treatment options during pre- and postoperative counseling.

摘要

背景

位于腮腺的肿瘤的首选治疗方法是手术。然而,术后并发症并不罕见。无论手术方式如何,最常见的并发症是味觉出汗综合征(FS)。传统上,FS包括患侧味觉性出汗以及腮腺区面部皮肤潮红。最近的研究描述了与FS相关的非典型不适。本研究的目的是评估腮腺良性肿瘤切除术后常见和非典型症状的晚期发生率及严重程度。

方法

我们进行了一项横断面研究,纳入了86名在研究前至少一年接受过腮腺浅叶切除术的受试者。问卷包括出汗-潮红-瘙痒-感觉异常-疼痛(SFIPP)味觉出汗综合征量表,并补充了关于症状的特定问题。

结果

86例中有67例(77.9%)报告了至少一种症状。最常见的症状是瘙痒(36/67 - 53.7%),其次是疼痛(35/67 - 52.2%),而28/67(41.8%)的受试者抱怨有非典型症状,无潮红或出汗。50/67(74.6%)的受试者表示希望治疗这种不适。

结论

腮腺切除术后晚期局部不适并不罕见,常见和“不常见”症状的发生率几乎相同。我们的结果表明,在术前和术后咨询期间告知患者该综合征的发生情况及可用治疗选择的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af08/10820002/7a1789b3a1bd/jpm-14-00096-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af08/10820002/9482d623f8ae/jpm-14-00096-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af08/10820002/7a1789b3a1bd/jpm-14-00096-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af08/10820002/9482d623f8ae/jpm-14-00096-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af08/10820002/7a1789b3a1bd/jpm-14-00096-g002.jpg

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本文引用的文献

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J Plast Reconstr Aesthet Surg. 2023 Oct;85:149-154. doi: 10.1016/j.bjps.2023.07.013. Epub 2023 Jul 8.
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Surgical management and side effects of parotid gland surgery for benign lesions: a retrospective analysis of our experience from 2012 to 2021.良性病变腮腺手术的外科治疗及并发症:2012 年至 2021 年回顾性分析。
Br J Oral Maxillofac Surg. 2023 Jul;61(6):411-415. doi: 10.1016/j.bjoms.2023.03.011. Epub 2023 Mar 31.
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The Minor's test in Frey syndrome treated with botulinum toxin: Methodology and efficacy.
Frey 综合征中小儿试验的肉毒毒素治疗:方法学和疗效。
Am J Otolaryngol. 2023 May-Jun;44(3):103818. doi: 10.1016/j.amjoto.2023.103818. Epub 2023 Feb 26.
4
Forehead and scalp gustatory sweating after temporomandibular joint surgery: an atypical presentation of Frey's syndrome.颞下颌关节手术后额部和头皮味觉性出汗:一种不典型的 Frey 综合征表现。
Clin Auton Res. 2023 Apr;33(2):201-203. doi: 10.1007/s10286-023-00931-3. Epub 2023 Feb 27.
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Auriculotemporal Frey syndrome not associated with surgery or diabetes: systematic review.不与手术或糖尿病相关的耳颞神经综合征:系统评价。
Eur J Pediatr. 2022 May;181(5):2127-2134. doi: 10.1007/s00431-022-04415-w. Epub 2022 Feb 19.
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Not only gustatory sweating and flushing: Signs and symptoms associated to the Frey syndrome and the role of botulinum toxin A therapy.不仅有味觉性出汗和潮红:与 Frey 综合征相关的症状和体征,以及肉毒毒素 A 治疗的作用。
Head Neck. 2021 Mar;43(3):949-955. doi: 10.1002/hed.26561. Epub 2020 Nov 28.
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Rising incidences of Warthin's tumors may be linked to obesity: a single-institutional experience.沃辛瘤发病率上升可能与肥胖有关:单机构经验
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Temporoparietal frey syndrome: An uncommon variant of a common syndrome.颞顶额眶部弗雷综合征:一种常见综合征的罕见变异。
Laryngoscope. 2019 Sep;129(9):2071-2075. doi: 10.1002/lary.27632. Epub 2018 Dec 20.
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Complications after parotid gland surgery Our experience.腮腺手术后的并发症 我们的经验
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