Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC, United States of America.
Wits Reproductive Health and HIV Institute, University of the Witwatersrand, Johannesburg, South Africa.
PLoS One. 2018 Dec 20;13(12):e0209114. doi: 10.1371/journal.pone.0209114. eCollection 2018.
Fertility intentions and contraceptive use are often not assessed in the context of clinical HIV care, representing a possible programming gap if women's family planning needs change over time. We aimed to identify longitudinal patterns of unmet need for contraception over a 12-month period among women living with HIV taking antiretroviral therapy (ART).
850 non-pregnant, HIV-positive women aged 18-35 on or initiating ART in Johannesburg, South Africa, were enrolled into a prospective cohort study in 2009-2010. Fertility intentions and contraceptive use were assessed during routine HIV care visits via an interviewer-administered questionnaire, and women were referred for on-site contraceptive counseling. We used group-based trajectory modeling to identify patterns of unmet need for contraception over 12 months, first in the entire population and then in a subset of recent ART initiators.
In the full population we identified four patterns of unmet need for contraception over one year. Half of the enrolled women were predicted to have a consistently high probability of unmet need, 22.9% a consistently low probability, 16.7% a decreasing probability, and 10.4% an increasing probability over time. Contraceptive method discontinuation and rapidly changing fertility intentions were the primary drivers of changing (increasing or decreasing) unmet need over follow-up. Results were similar in recent ART initiators.
Half of women were estimated to have a high probability of unmet need that persisted over time, and more than a quarter were estimated to experience patterns of changing unmet need over 12 months. Family planning needs should be assessed more regularly in HIV-positive women to prevent unintended pregnancies and support safer conception among women trying to conceive.
在临床艾滋病毒护理中,通常不会评估生育意愿和避孕措施的使用情况,如果女性的计划生育需求随时间发生变化,这可能代表存在一个方案规划缺口。我们旨在确定在接受抗逆转录病毒治疗(ART)的艾滋病毒感染者中,在 12 个月的时间内,避孕需求未得到满足的纵向模式。
2009-2010 年,在南非约翰内斯堡,对 850 名年龄在 18-35 岁之间、正在接受或开始接受 ART 的非妊娠艾滋病毒阳性妇女进行了前瞻性队列研究。通过访谈员管理的问卷调查,在常规艾滋病毒护理就诊期间评估生育意愿和避孕措施的使用情况,为有需要的妇女提供现场避孕咨询。我们使用基于群组的轨迹建模来确定 12 个月内避孕需求未得到满足的模式,首先在整个人群中进行,然后在最近开始接受 ART 的亚组中进行。
在整个人群中,我们确定了一年中避孕需求未得到满足的四种模式。一半的入组妇女预计避孕需求未得到满足的可能性一直较高,22.9%的妇女避孕需求未得到满足的可能性一直较低,16.7%的妇女避孕需求未得到满足的可能性逐渐降低,10.4%的妇女避孕需求未得到满足的可能性逐渐增加。避孕方法的停止和快速变化的生育意愿是随访期间未满足的需求变化(增加或减少)的主要驱动因素。在最近开始接受 ART 的人群中,结果相似。
预计有一半的妇女避孕需求未得到满足的可能性一直较高,超过四分之一的妇女预计在 12 个月内避孕需求未得到满足的模式会发生变化。应该更定期地评估艾滋病毒阳性妇女的计划生育需求,以防止意外怀孕,并支持试图怀孕的妇女进行更安全的受孕。