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[使用格鲁利希和派尔方法进行放射学骨龄测定与使用BoneXpert软件进行自动评估之间的相关性]

[Correlation in radiological bone age determination using the Greulich and Pyle method versus automated evaluation using BoneXpert software].

作者信息

Pose Lepe Georgette, Villacrés Fabián, Silva Fuente-Alba Claudio, Guiloff Stefan

机构信息

Departamento de Imágenes, Clínica Alemana de Santiago, Chile.

Facultad de Medicina, Clínica Alemana de Santiago, Universidad del Desarrollo, Chile.

出版信息

Rev Chil Pediatr. 2018 Oct;89(5):606-611. doi: 10.4067/S0370-41062018005000705.

Abstract

OBJECTIVE

To determine the degree of correlation in the radiological bone age assessment using the Greulich and Pyle method versus automated assessment through BoneXpert® software between 2013 and 2016.

MATERIAL AND METHOD

Correlation study of diagnostic techniques of 1500 carpal X-rays to assess bone age in patients under 16 years of age from Clínica Alemana de Santiago. X-rays with bone age assessment using the Atlas of Greulich and Pyle (GP) by 1 out of 7 pediatric radiologists, were analyzed using the BoneXpert (BE) software for automated bone age assessment. 100 cases were taken at random for analysis/re-analysis using the BoneXpert method to determine its accuracy. The level of correlation of the measurements was analyzed using the correlation coefficient (Pearson's r) and the variability of the measurements using the Bland-Altman analysis.

RESULTS

1493 cases were assessed, seven were excluded due to failure in the X-ray technique, 922 females (61.8%), with a median chronological age of 9.96 years and 11.12 years for males (p 0.001). The correlation between manual bone age (GP) and automated bone age using BoneXpert method among radiologists ran ged from 0.91 to 0.93. The Bland-Altman analysis indicated an average difference between manual bone age and bone age using the BoneXpert method of 0.19 years (CI 0.13 to 0.25). In the analysis/ re-analysis of 100 random cases using the BoneXpert software, the correlation was 1.00 (100% accu racy).

CONCLUSION

The automated analysis using BoneXpert allows for standardized, low-variability, and high-concordance assessment.

摘要

目的

确定2013年至2016年间,使用格-派(Greulich and Pyle)方法进行的放射学骨龄评估与通过BoneXpert®软件进行的自动评估之间的相关程度。

材料与方法

对来自圣地亚哥德国诊所的1500例16岁以下患者的腕部X线片进行骨龄评估诊断技术的相关性研究。由7名儿科放射科医生中的1名使用格-派图谱(GP)对X线片进行骨龄评估,并使用BoneXpert(BE)软件进行自动骨龄评估分析。随机选取100例病例,使用BoneXpert方法进行分析/重新分析以确定其准确性。使用相关系数(Pearson's r)分析测量的相关水平,并使用布兰德-奥特曼(Bland-Altman)分析测量的变异性。

结果

共评估1493例病例,7例因X线技术失败被排除,其中女性922例(61.8%),年龄中位数为9.96岁,男性为11.12岁(p<0.001)。放射科医生使用手工骨龄(GP)与使用BoneXpert方法的自动骨龄之间的相关性范围为0.91至0.93。布兰德-奥特曼分析表明,手工骨龄与使用BoneXpert方法的骨龄之间的平均差异为0.19岁(可信区间为0.13至0.25)。在使用BoneXpert软件对100例随机病例进行的分析/重新分析中,相关性为1.00(准确率100%)。

结论

使用BoneXpert进行自动分析可实现标准化、低变异性和高一致性的评估。

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