成人癌症幸存者自我管理干预措施的效果和组成部分：系统评价和计划荟萃分析的方案。

Effectiveness and components of self-management interventions in adult cancer survivors: a protocol for a systematic review and planned meta-analysis.

机构信息

University of Calgary, Cumming School of Medicine, Department of Oncology, Calgary, Canada.

出版信息

Syst Rev. 2018 Dec 20;7(1):238. doi: 10.1186/s13643-018-0902-7.

DOI:10.1186/s13643-018-0902-7

PMID:30572935

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6300917/

Abstract

BACKGROUND

Self-management interventions have been proposed as effective strategies to improve health and well-being and promote optimal coping in cancer survivors. Several reviews have shown benefits of self-management interventions on a variety of patient-reported outcomes. Effective self-management strategies in other chronic disease populations are typically based on theories of behavior change, but the extent of theoretical underpinnings in cancer self-management programs has not been evaluated to date. Our aim is to expand on previous reviews by evaluating the effectiveness of self-management interventions in cancer survivors as well as the theoretical components of such interventions.

METHODS

We will conduct a systematic review of self-management interventions for adults who have completed primary treatment for their solid or hematological cancer. Interventions tested using experimental or quasi-experimental methods, with any type of comparator, will be included. A search strategy will be designed with a health sciences librarian and then performed using MEDLINE, EMBASE, PsycINFO, CINAHL, Scopus, the Cochrane database of systematic reviews, the National Institutes of Health clinical trials registry, and the Cochrane CENTRAL registry of controlled trials. Data synthesis will include a narrative and tabular summary of the results. Appropriate statistical analysis may include a meta-analysis using random effects methods to determine the effectiveness of self-management interventions and a meta-regression to evaluate how characteristics of the interventions are associated with the intervention effect. Risk of bias will be evaluated using the Cochrane risk of bias tool or the Risk of Bias in Non-randomized studies tool (RoBANS).

DISCUSSION

The results of this systematic review will add to previous reviews and expand the existing knowledge base of the effectiveness and active components of self-management interventions for adult cancer survivors.

SYSTEMATIC REVIEW REGISTRATION

PROSPERO CRD42018085300.

摘要

背景

自我管理干预措施被认为是改善健康和幸福感、促进癌症幸存者最佳应对的有效策略。有几项综述表明，自我管理干预措施对各种患者报告的结果都有好处。在其他慢性疾病患者群体中，有效的自我管理策略通常基于行为改变理论，但迄今为止，尚未评估癌症自我管理计划中理论基础的程度。我们的目的是通过评估癌症幸存者自我管理干预措施的有效性以及此类干预措施的理论组成部分，对以前的综述进行扩展。

方法

我们将对已完成实体瘤或血液系统癌症主要治疗的成年人的自我管理干预措施进行系统评价。将纳入使用实验或准实验方法测试的干预措施，以及任何类型的对照。将与健康科学图书馆员一起设计搜索策略，然后使用 MEDLINE、EMBASE、PsycINFO、CINAHL、Scopus、Cochrane 系统评价数据库、美国国立卫生研究院临床试验注册处和 Cochrane 对照试验中心注册处进行搜索。数据综合将包括结果的叙述性和表格总结。适当的统计分析可能包括使用随机效应方法进行的荟萃分析，以确定自我管理干预措施的有效性，以及元回归以评估干预措施的特征与干预效果的关系。使用 Cochrane 偏倚风险工具或非随机研究偏倚风险工具（RoBANS）评估偏倚风险。