Nursing Teaching and Research Section, Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
Department of Computing, The Hong Kong Polytechnic University, Hong Kong, China.
BMJ Open. 2022 Feb 16;12(2):e053745. doi: 10.1136/bmjopen-2021-053745.
Breast cancer is the leading cause of global cancer incidence and represents 11.7% of all new cancer cases. However, breast cancer survivors (BCS) suffer from many intense physical and psychological symptoms, functional deficits and adverse effects during and after treatment, significantly affecting their quality of life. Virtual reality (VR) technology uses computer technology to create an interactive three-dimensional world by visual, audio and touch simulation and is being used in breast cancer rehabilitation management. This paper reports on the protocol for a systematic review and meta-analysis exploring the efficacy of VR-based interventions in the rehabilitation management of BCS.
This protocol for conducting a systematic review and meta-analysis was prepared according to the recommendations of the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols 2015 statement. Web of Science, PubMed, Embase, CINAHL, Cochrane Central Register of Controlled Trials, CNKI, Wanfang, VIP and SinoMed will be used in the search. The search will include randomised controlled trials, quasi-experimental studies and case-controlled trials published in English and Chinese. Further, the risk of bias of the studies included in the systematic review and meta-analysis will be assessed using the Cochrane risk-of-bias tool. The statistical program Review Manager V.5.3 will be used in the meta-analysis. The I² test will be used to determine statistical heterogeneity among the included studies.
Ethics approval will not be needed because the data to be used in this systematic review and meta-analysis will be extracted from published studies. The systematic review and meta-analysis will focus on whether VR-based interventions are effective in the rehabilitation management of BCS. It will be disseminated by publication in a peer-reviewed journal.
CRD42021250727.
乳腺癌是全球癌症发病率的主要原因，占所有新发癌症病例的 11.7%。然而，乳腺癌幸存者（BCS）在治疗期间和治疗后会遭受许多强烈的身体和心理症状、功能缺陷和不良反应，这显著影响了他们的生活质量。虚拟现实（VR）技术使用计算机技术通过视觉、音频和触觉模拟创建一个交互的三维世界，并正在用于乳腺癌康复管理。本文报告了一项系统评价和荟萃分析的方案，该方案旨在探索基于 VR 的干预措施在 BCS 康复管理中的疗效。
本系统评价和荟萃分析方案是根据 2015 年首选报告项目的系统评价和荟萃分析协议建议制定的。将在 Web of Science、PubMed、Embase、CINAHL、Cochrane 中央对照试验注册中心、CNKI、万方、VIP 和 SinoMed 中进行搜索。搜索将包括英语和中文发表的随机对照试验、准实验研究和病例对照试验。此外，将使用 Cochrane 偏倚风险工具评估系统评价和荟萃分析中纳入研究的偏倚风险。Meta 分析将使用 Review Manager V.5.3 统计程序。将使用 I² 检验来确定纳入研究之间的统计学异质性。
由于本系统评价和荟萃分析中使用的数据将从已发表的研究中提取，因此不需要伦理批准。系统评价和荟萃分析将重点关注基于 VR 的干预措施在 BCS 康复管理中的有效性。它将通过在同行评议期刊上发表来传播。
PROSPERO 注册号：CRD42021250727。
