Formiga Magno F, Vital Isabel, Urdaneta Gisel, Balestrini Kira, Cahalin Lawrence P, Campos Michael A
Department of Physical Therapy, Miller School of Medicine, University of Miami, Coral Gables, FL, USA.
CAPES Foundation, Ministry of Education of Brazil, Brasilia, Brazil.
SAGE Open Med. 2018 Dec 12;6:2050312118819015. doi: 10.1177/2050312118819015. eCollection 2018.
The Test of Incremental Respiratory Endurance is a novel testing method that provides a unique examination of one's inspiratory muscle strength, work and endurance. Little is known about the relationship between inspiratory muscle performance and mortality risk in obstructive lung disease. We examined the relationship between the Test of Incremental Respiratory Endurance measures and the Body-mass index, airflow Obstruction, Dyspnea and Exercise index in chronic obstructive pulmonary disease.
In all, 70 males with mild-to-very severe chronic obstructive pulmonary disease (mean ± standard deviation of 70.2 ± 5.9 years) underwent measurements of body-mass index, spirometry, dyspnea and a 6-min walk test from which the Body-mass index, airflow Obstruction, Dyspnea and Exercise score was calculated. The Test of Incremental Respiratory Endurance provided measures of maximal inspiratory pressure, sustained maximal inspiratory pressure and inspiratory duration.
All Test of Incremental Respiratory Endurance parameters inversely correlated with the Body-mass index, airflow Obstruction, Dyspnea and Exercise score: maximal inspiratory pressure (r = -0.355, p = 0.00), sustained maximal inspiratory pressure (r = -0.426, p = 0.00) and ID (r = -0.278, p = 0.02), with sustained maximal inspiratory pressure displaying the highest correlation. Independent significant correlations were also observed between the sustained maximal inspiratory pressure and all Body-mass index, airflow Obstruction, Dyspnea and Exercise score components, except for body-mass index. Finally, sustained maximal inspiratory pressure was significantly different among the Body-mass index, airflow Obstruction, Dyspnea and Exercise index quartiles.
The significant association between the Body-mass index, airflow Obstruction, Dyspnea and Exercise score and inspiratory muscle performance, in particular sustained maximal inspiratory pressure, suggests that these measures may have a potential prognostic value in the evaluation of chronic obstructive pulmonary disease.
递增呼吸耐力测试是一种新型测试方法，可对一个人的吸气肌力量、功和耐力进行独特的检测。关于阻塞性肺病中吸气肌功能与死亡风险之间的关系，人们知之甚少。我们研究了递增呼吸耐力测试指标与慢性阻塞性肺疾病患者的体重指数、气流阻塞、呼吸困难和运动指数之间的关系。
总共70名患有轻度至重度慢性阻塞性肺疾病的男性（平均年龄±标准差为70.2±5.9岁）接受了体重指数、肺活量测定、呼吸困难评估以及6分钟步行测试，并据此计算出体重指数、气流阻塞、呼吸困难和运动评分。递增呼吸耐力测试提供了最大吸气压力、持续最大吸气压力和吸气持续时间的测量值。
所有递增呼吸耐力测试参数均与体重指数、气流阻塞、呼吸困难和运动评分呈负相关：最大吸气压力（r = -0.355，p = 0.00）、持续最大吸气压力（r = -0.426，p = 0.00）和吸气持续时间（r = -0.278，p = 0.02），其中持续最大吸气压力的相关性最高。除体重指数外，持续最大吸气压力与体重指数、气流阻塞、呼吸困难和运动评分的所有组成部分之间也存在独立的显著相关性。最后，持续最大吸气压力在体重指数、气流阻塞、呼吸困难和运动指数四分位数之间存在显著差异。
体重指数、气流阻塞、呼吸困难和运动评分与吸气肌功能，特别是持续最大吸气压力之间的显著关联表明，这些指标在评估慢性阻塞性肺疾病时可能具有潜在的预后价值。
