Pauri F, Pierelli F, Fiermonte G, Giacomini P, Cupini L M, Morocutti C
Istituto di Clinica delle Malattie Nervose e Mentali, Università La Sapienza, Roma.
Riv Neurol. 1988 Jul-Aug;58(4):156-63.
The authors show the clinical characteristics of the cluster headache and consider the main physiopathogenetic hypothesis that could explain the polyhedric symptomatology of this kind of headache. They point out at first the hypothesis of an imbalance in the autonomic nervous system, sympathetic-parasympathetic, then they discuss about the theory of a disregulation of nociceptive system proposed by Sicuteri, at the end they hypothesize an alteration at the superior integrative level, probably the hypothalamic-limbic one.
作者展示了丛集性头痛的临床特征，并思考了可解释这类头痛多方面症状的主要生理病理假说。他们首先指出自主神经系统（交感神经 - 副交感神经）失衡的假说，接着讨论了西库泰里提出的伤害感受系统调节紊乱理论，最后他们推测在高级整合水平，可能是下丘脑 - 边缘系统水平存在改变。
