Division of Pediatric Anesthesia, Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina.
Division of Neonatology, Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina.
Am J Perinatol. 2019 Oct;36(12):1243-1249. doi: 10.1055/s-0038-1676591. Epub 2018 Dec 21.
To describe the variation in surgical gastrostomy tube (SGT) placement in premature infants among neonatal intensive care units (NICUs) in the United States.
We identified 8,781 premature infants discharged from 114 NICUs in the Pediatrix Medical Group from 2010 to 2012. The outcome of interest was SGT placement prior to discharge home from an NICU. Unadjusted proportions and adjusted risk estimates were calculated to quantify variation observed among individual NICUs.
SGT placement occurred in 360 of 8,781 (4.1%) of infants. Across NICUs, any gastrostomy tube placement ranged from none in 45 NICUs up to 19.6%. Adjusted risk estimates for factors associated with SGT placement included gestational age at birth (odds ratio [OR]: 0.7/week, 95% confidence interval[CI]: [0.65, 0.75]), small for gestational age status (OR: 2.78 [2.09, 3.71]), administration of antenatal steroids (OR: 0.69 [0.52, 0.92]), Hispanic ethnicity (OR: 0.54 [0.37, 0.78]), and higher 5-minute Apgar scores (7-10, OR: 0.54 [0.37, 0.79]).
Individual NICU center has a strong clinical effect on the probability of SGT placement relative to other medical factors. Future work is needed to understand the cause of this variation and the degree to which it represents over or under use of gastrostomy tubes.
描述美国新生儿重症监护病房(NICU)中早产儿外科胃造口管(SGT)放置的变化。
我们确定了 2010 年至 2012 年期间,来自 Pediatrix Medical Group 的 114 家 NICU 出院的 8781 名早产儿。感兴趣的结局是 NICU 出院前 SGT 的放置。计算了未调整的比例和调整后的风险估计值,以量化个体 NICU 之间观察到的变异。
在 8781 名婴儿中,有 360 名(4.1%)进行了 SGT 放置。在 NICU 之间,任何胃造口管放置的范围从 45 个 NICU 中没有放置到 19.6%。与 SGT 放置相关的因素的调整风险估计包括出生时的胎龄(比值比[OR]:0.7/周,95%置信区间[CI]:[0.65,0.75])、小于胎龄儿状态(OR:2.78 [2.09,3.71])、产前类固醇的使用(OR:0.69 [0.52,0.92])、西班牙裔(OR:0.54 [0.37,0.78])和较高的 5 分钟 Apgar 评分(7-10,OR:0.54 [0.37,0.79])。
相对于其他医疗因素,个体 NICU 中心对 SGT 放置的概率有很强的临床影响。需要进一步研究以了解这种变异的原因以及它在多大程度上代表胃造口管的过度或不足使用。