Jonas Children's Vision Care, Bernard & Shirlee Brown Glaucoma Laboratory, Columbia Stem Cell Initiative-Departments of Ophthalmology, Biomedical Engineering, Pathology & Cell Biology, Institute of Human Nutrition, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Department of Ophthalmology, Columbia University, Edward S. Harkness Eye Institute, NewYork-Presbyterian Hospital, New York, NY, USA.
Adv Exp Med Biol. 2018;1085:219-221. doi: 10.1007/978-3-319-95046-4_46.
Syphilis is an infectious disease caused by a spirochete, Treponema pallidum; it is most commonly spread by sexual transmission. Syphilis is known as the "Great Imitator," as systemic manifestations are variable. It can involve any part of the eye, with syphilitic uveitis being the most common type. Congenital syphilis is characterized by Hutchinson's teeth, saddle nose deformity, deafness, and interstitial keratitis; pigmentary changes in the retina are varied and patchy.
梅毒是一种由螺旋体苍白密螺旋体引起的传染病;它最常通过性传播。梅毒被称为“伟大的模仿者”,因为全身表现多种多样。它可以涉及眼睛的任何部位,其中梅毒性葡萄膜炎是最常见的类型。先天性梅毒的特征是哈钦森牙、鞍鼻畸形、耳聋和间质性角膜炎;视网膜色素变化多种多样且呈斑片状。