Streight Kaitlyn L, Paranal Ronald M, Musher Daniel M
Baylor College of Medicine, 1 Baylor Plaza, Houston, TX, 77030, USA.
J Med Case Rep. 2019 Jul 26;13(1):227. doi: 10.1186/s13256-019-2171-z.
Syphilis is a sexually transmitted bacterial infection of the spirochete, Treponema pallidum. While primary syphilis often involves genitalia, oral manifestations are observed in a subset of patients. These lesions are often associated with submandibular and cervical lymphadenopathy. This is a case report of a primary syphilitic lesion located on the hard palate of the oral cavity, with only a very few cases described previously.
We describe a rare case of syphilis in a 59-year-old African American man presenting with subjective fevers, chills, marked submental lymphadenopathy, a diffuse skin rash, and an ulcer of the hard palate.
This case report demonstrates the importance of maintaining a high index of suspicion for syphilitic infection when a patient presents with nonspecific symptoms, a diffuse rash, and an oral lesion.
梅毒是由梅毒螺旋体引起的一种性传播细菌感染。虽然一期梅毒常累及生殖器，但部分患者会出现口腔表现。这些病变常伴有下颌下和颈部淋巴结病。本文报告一例位于口腔硬腭的一期梅毒病变，此前仅有极少数病例报道。
我们描述了一例罕见的梅毒病例，患者为一名59岁的非裔美国男性，有主观发热、寒战、显著的颏下淋巴结病、弥漫性皮疹以及硬腭溃疡。
本病例报告表明，当患者出现非特异性症状、弥漫性皮疹和口腔病变时，高度怀疑梅毒感染具有重要意义。
