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先天性梅毒伴哈钦森三联征的临床特征。

Clinical aspects of congenital syphilis with Hutchinson's triad.

作者信息

Pessoa Larissa, Galvão Virgilio

机构信息

Department of Medical Sciences, University of Brasilia, Brasília, Brazil.

出版信息

BMJ Case Rep. 2011 Dec 21;2011:bcr1120115130. doi: 10.1136/bcr.11.2011.5130.

DOI:10.1136/bcr.11.2011.5130
PMID:22670010
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3246168/
Abstract

Congenital syphilis is an infectious disease caused by Treponema pallidum transmitted by infected mother to her baby during pregnancy. Late congenital syphilis is recognised with 2 or more years after birth. One of the main aspects is observed with the triad of Hutchinson, characterised by the presence of interstitial keratitis, eighth nerve deafness and Hutchinson's teeth. This manuscript reports a case of late congenital syphilis presenting with Hutchinson's triad at an age of 7 years. These clinical features are related to syphilis present during pregnancy and at birth, however they commonly become apparent after 5-years of age.

摘要

先天性梅毒是一种由梅毒螺旋体引起的传染病，孕期受感染的母亲会将其传染给胎儿。晚期先天性梅毒在出生后2年或更久才被发现。主要特征之一是哈钦森三联征，表现为间质性角膜炎、第八对脑神经耳聋和哈钦森牙。本文报告了一例7岁时出现哈钦森三联征的晚期先天性梅毒病例。这些临床特征与孕期及出生时存在的梅毒有关，但通常在5岁以后才会明显显现。

相似文献

1
Clinical aspects of congenital syphilis with Hutchinson's triad.先天性梅毒伴哈钦森三联征的临床特征。
BMJ Case Rep. 2011 Dec 21;2011:bcr1120115130. doi: 10.1136/bcr.11.2011.5130.
2
Syphilis.梅毒。
Adv Exp Med Biol. 2018;1085:219-221. doi: 10.1007/978-3-319-95046-4_46.
3
[A case of keratitis, ichthyosis, and deafness syndrome with Hutchinson's triad-like symptoms].[一例伴有类似哈钦森三联征症状的角膜炎、鱼鳞病和耳聋综合征]
Nippon Ganka Gakkai Zasshi. 1999 Apr;103(4):322-6.
4
Premature loss of primary teeth associated with congenital syphilis: a case report.先天性梅毒相关的乳牙过早脱落：一例报告
J Clin Pediatr Dent. 2005 Spring;29(3):273-6. doi: 10.17796/jcpd.29.3.m671132x8r306278.
5
Early detection of congenital syphilis.先天性梅毒的早期检测。
J Indian Soc Pedod Prev Dent. 2014 Oct-Dec;32(4):333-7. doi: 10.4103/0970-4388.140969.
6
Acquired syphilis in a patient with late congenital syphilis.晚期先天性梅毒患者的获得性梅毒。
Sex Transm Dis. 1987 Apr-Jun;14(2):119-21. doi: 10.1097/00007435-198704000-00014.
7
[Hutchinson's syndrome].[哈钦森综合征]
Jibiinkoka. 1967 Dec;39(12):1299.
8
Testing for congenital syphilis in interstitial keratitis.间质性角膜炎中先天性梅毒的检测
Am J Ophthalmol. 1971 Oct;72(4):816-20. doi: 10.1016/0002-9394(71)90023-7.
9
A case of congenital syphilis with Hutchinson's triad.一例伴有哈钦森三联征的先天性梅毒病例。
Indian J Sex Transm Dis AIDS. 2011 Jan;32(1):34-6. doi: 10.4103/0253-7184.81252.
10
[Hutchinson's syndrome].[哈钦森综合征]
Nihon Rinsho. 1977 Spring;35 Suppl 1:1208-9.

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A Case of Congenital Syphilis Presenting with Unusual Skin Eruptions.一例以罕见皮疹为表现的先天性梅毒病例。
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本文引用的文献

1
A case of congenital syphilis with Hutchinson's triad.一例伴有哈钦森三联征的先天性梅毒病例。
Indian J Sex Transm Dis AIDS. 2011 Jan;32(1):34-6. doi: 10.4103/0253-7184.81252.
2
Syphilis, still a major cause of infant mortality.梅毒仍是婴儿死亡的主要原因。
Lancet Infect Dis. 2011 Sep;11(9):654-5. doi: 10.1016/S1473-3099(11)70150-5. Epub 2011 Jun 15.
3
Lives Saved Tool supplement detection and treatment of syphilis in pregnancy to reduce syphilis related stillbirths and neonatal mortality.生命挽救工具补充了梅毒孕妇的检测和治疗，以降低梅毒相关的死产和新生儿死亡率。
BMC Public Health. 2011 Apr 13;11 Suppl 3(Suppl 3):S9. doi: 10.1186/1471-2458-11-S3-S9.
4
The contribution of laboratory investigations in diagnosis of congenital infections.实验室检查在先天性感染诊断中的作用。
Rom J Morphol Embryol. 2011;52(1 Suppl):481-4.
5
Prevalence of toxoplasmosis, HIV, syphilis and rubella in a population of puerperal women using Whatman 903 filter paper.应用 Whatman 903 滤纸检测产褥期妇女弓形虫病、艾滋病、梅毒和风疹的流行情况。
Braz J Infect Dis. 2010 Jan-Feb;14(1):24-9. doi: 10.1590/s1413-86702010000100006.
6
Tooth Buds and Jaws in Patients with Congenital Syphilis: Correlation between Distribution of Treponema pallidum and Tissue Reaction.先天性梅毒患者的牙胚与颌骨：梅毒螺旋体分布与组织反应的相关性
Am J Pathol. 1944 Mar;20(2):297-319.
7
Congenital syphilis, still a reality in 21st century: a case report.先天性梅毒在21世纪仍然存在：一例病例报告。
J Med Case Rep. 2007 Sep 19;1:90. doi: 10.1186/1752-1947-1-90.
8
Syphilis in children: congenital and acquired.儿童梅毒：先天性和后天性。
Semin Pediatr Infect Dis. 2005 Oct;16(4):245-57. doi: 10.1053/j.spid.2005.06.005.
9
Premature loss of primary teeth associated with congenital syphilis: a case report.先天性梅毒相关的乳牙过早脱落：一例报告
J Clin Pediatr Dent. 2005 Spring;29(3):273-6. doi: 10.17796/jcpd.29.3.m671132x8r306278.
10
Dental defects of congenital syphilis.先天性梅毒的牙齿缺陷
Am J Phys Anthropol. 1998 Sep;107(1):25-40. doi: 10.1002/(SICI)1096-8644(199809)107:1<25::AID-AJPA3>3.0.CO;2-C.