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认知行为疗法对客观睡眠时间短和正常的失眠患者同样有效。

Cognitive behavioral treatment for insomnia is equally effective in insomnia patients with objective short and normal sleep duration.

机构信息

Department of Psychiatry and Psychotherapy, University of Regensburg, Germany.

Department of Psychiatry and Psychotherapy, University of Regensburg, Germany.

出版信息

Sleep Med. 2020 Feb;66:271-275. doi: 10.1016/j.sleep.2018.10.038. Epub 2018 Nov 26.

Abstract

BACKGROUND

It has been suggested that insomnia patients with short sleep duration and insomnia patients with normal sleep duration may respond differently to cognitive behavioral treatment for insomnia (CBT-I). To evaluate this hypothesis, we retrospectively examined a large sample of patients with chronic insomnia regarding their outcome post-treatment and six months after participating in a two-week standardized inpatient CBT-I program.

OBJECTIVES

Seventy-two women and 20 men with chronic insomnia received standardized inpatient CBT-I and were examined with three nights of polysomnography (two baseline nights and one post-treatment night directly following the two-week treatment). Follow-up measurements of subjective insomnia symptoms were conducted after six months. The CBT-I outcome was compared between insomnia patients with polysomnographically determined short (< 6 h) and normal (≥ 6 h) sleep duration.

RESULTS

Concerning subjective outcomes, CBT-I was equally effective in insomnia patients with objective short and normal sleep duration. Secondary analyses of polysomnographic data collected at post-treatment revealed that insomnia patients with short sleep duration showed a better treatment response in comparison to those with normal sleep duration.

CONCLUSIONS

These results suggest that the distinction in insomnia between objective short and normal sleep duration may be of limited value for treatment decisions regarding CBT-I. However, as the overall picture of the literature on this issue is not conclusive, we conclude that further prospective research is necessary to investigate the clinical validity of phenotyping insomnia patients by objective sleep data.

摘要

背景

有人提出,睡眠持续时间短的失眠患者和睡眠持续时间正常的失眠患者对失眠认知行为治疗(CBT-I)的反应可能不同。为了验证这一假设,我们回顾性地对大量慢性失眠患者进行了研究,评估他们在接受为期两周的标准化住院 CBT-I 治疗后的治疗效果和六个月后的随访情况。

目的

72 名女性和 20 名男性慢性失眠患者接受了标准化住院 CBT-I,并接受了三晚多导睡眠图(基线两晚和治疗两周后直接进行的一晚)检查。六个月后进行主观失眠症状的随访测量。比较了多导睡眠图确定的短睡眠时间(<6 小时)和正常睡眠时间(≥6 小时)的失眠患者的 CBT-I 结果。

结果

就主观结果而言,CBT-I 对客观睡眠时间短和正常的失眠患者同样有效。在治疗后收集的多导睡眠图数据的二次分析中发现,与睡眠正常的失眠患者相比,睡眠持续时间短的失眠患者的治疗反应更好。

结论

这些结果表明,在 CBT-I 治疗决策中,将失眠患者的客观睡眠时间与正常睡眠时间进行区分可能价值有限。然而,由于关于这一问题的文献总体情况并不明确,我们得出结论,需要进一步进行前瞻性研究,以调查通过客观睡眠数据对失眠患者进行表型分析的临床有效性。

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