St. Joseph University, Faculty of Medicine, Beirut, Lebanon.
The Smith Institute for Urology, Zucker School of Medicine Hofstra/Northwell, New Hyde Park, NY.
Urol Oncol. 2019 Mar;37(3):219-226. doi: 10.1016/j.urolonc.2018.11.020. Epub 2018 Dec 19.
Lymph node dissection is part of the standard treatment protocol for various cancers, but its role in prostate cancer has been debatable for some time. Pelvic lymphadenectomy has been shown to better help stage prostate cancer patients, but has yet to be definitively proven to be of any benefit for survival. Various templates for lymph node dissections exist, and though some national guidelines have endorsed an extended pelvic node dissection, the choice of template is still controversial. Pelvic lymphadenectomy may lead to a slightly higher rate complications and operative time, and their use must be judiciously applied to patients with a high enough risk of lymph node involvement. We present a comprehensive review of the literature regarding the benefits and harms of lymph node dissection in prostate cancer.
淋巴结清扫术是各种癌症标准治疗方案的一部分,但一段时间以来,其在前列腺癌中的作用一直存在争议。盆腔淋巴结清扫术已被证明可以更好地帮助分期前列腺癌患者,但尚未明确证明对生存有益。存在各种淋巴结清扫模板,尽管一些国家指南已经认可了扩大的盆腔淋巴结清扫,但模板的选择仍存在争议。盆腔淋巴结清扫术可能会导致并发症和手术时间略有增加,并且必须谨慎地将其应用于淋巴结受累风险足够高的患者。我们对有关前列腺癌中淋巴结清扫的益处和危害的文献进行了全面回顾。