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淋巴结清扫术在前列腺癌中的应用:我们目前的状况如何?

Utility of Lymphadenectomy in Prostate Cancer: Where Do We Stand?

作者信息

Małkiewicz Bartosz, Kiełb Paweł, Karwacki Jakub, Czerwińska Róża, Długosz Paulina, Lemiński Artur, Nowak Łukasz, Krajewski Wojciech, Szydełko Tomasz

机构信息

University Center of Excellence in Urology, Department of Minimally Invasive and Robotic Urology, Wroclaw Medical University, 50-556 Wroclaw, Poland.

Department of Urology and Urological Oncology, Pomeranian Medical University, Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland.

出版信息

J Clin Med. 2022 Apr 22;11(9):2343. doi: 10.3390/jcm11092343.

DOI:10.3390/jcm11092343
PMID:35566471
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9103547/
Abstract

The purpose of this review is to summarize the current knowledge on lymph node dissection (LND) in prostate cancer (PCa) patients undergoing radical prostatectomy (RP). Despite a growing body of evidence, the utility and therapeutic and prognostic value of such an approach, as well as the optimal extent of LND, remain unsolved issues. Although LND is the most accurate staging procedure, the direct therapeutic effect is still not evident from the current literature, which limits the possibility of establishing clear recommendations. This indicates the need for further robust and adequately designed high-quality clinical trials.

摘要

本综述的目的是总结目前关于接受根治性前列腺切除术(RP)的前列腺癌(PCa)患者淋巴结清扫术(LND)的相关知识。尽管证据越来越多,但这种方法的实用性、治疗和预后价值以及LND的最佳范围仍然是未解决的问题。虽然LND是最准确的分期程序,但目前的文献中其直接治疗效果仍不明显,这限制了制定明确建议的可能性。这表明需要进一步开展强有力且设计充分的高质量临床试验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/196b/9103547/7e121051e50f/jcm-11-02343-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/196b/9103547/7e121051e50f/jcm-11-02343-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/196b/9103547/7e121051e50f/jcm-11-02343-g001.jpg

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Limited versus Extended Pelvic Lymph Node Dissection for Prostate Cancer: A Randomized Clinical Trial.
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