Lippi Giuseppe, Cadamuro Janne
Section of Clinical Biochemistry, University of Verona Verona, Italy.
Department of Laboratory Medicine, Paracelsus Medical University Salzburg, Austria.
J Med Biochem. 2017 Oct 28;36(4):293-300. doi: 10.1515/jomb-2017-0029. eCollection 2017 Oct.
The preanalytical phase is crucial for assuring the quality of in vitro diagnostics. The leading aspects which contribute to enhance the vulnerability of this part of the total testing process include the lack of standardization of different practices for collecting, managing, transporting and processing biological specimens, the insufficient compliance with available guidelines and the still considerable number of preventable human errors. As in heavy industry, road traffic and aeronautics, technological advancement holds great promise for decreasing the risk of medical and diagnostic errors, thus including those occurring in the extra-analytical phases of the total testing process. The aim of this article is to discuss some potentially useful technological advances, which are not yet routine practice, but may be especially suited for improving the quality of the preanalytical phase in the future. These are mainly represented by introduction of needlewielding robotic phlebotomy devices, active blood tubes, drones for biological samples transportation, innovative approaches for detecting spurious hemolysis and preanalytical errors recording software products.
分析前阶段对于确保体外诊断的质量至关重要。导致整个检测过程这一部分易受影响的主要因素包括:生物样本采集、管理、运输和处理的不同操作缺乏标准化,对现有指南的依从性不足,以及仍有相当数量可预防的人为错误。与重工业、道路交通和航空领域一样,技术进步有望降低医疗和诊断错误的风险,从而减少整个检测过程分析外阶段出现的错误。本文旨在探讨一些可能有用的技术进步,这些技术尚未成为常规做法,但未来可能特别适合提高分析前阶段的质量。这些主要体现在引入持针机器人采血设备、有源采血管、用于生物样本运输的无人机、检测假性溶血的创新方法以及分析前错误记录软件产品。