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剖宫产术后缝线和敷料去除的时机(SCARR 研究)。

Timing of staples and dressing removal after cesarean delivery (the SCARR study).

机构信息

Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Department of Nursing Administration, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

出版信息

Int J Gynaecol Obstet. 2019 Mar;144(3):283-289. doi: 10.1002/ijgo.12757. Epub 2019 Jan 11.

DOI:10.1002/ijgo.12757
PMID:30582610
Abstract

OBJECTIVE

To investigate optimal timing of dressing and staples removal after cesarean delivery (CD).

METHODS

This prospective clustered clinical trial enrolled women undergoing CD between January 1, 2013, and October 31, 2014, at Hadassah-Hebrew University Hospital, Jerusalem. Women were assigned to one of five clusters differing in timing of dressing and staples removal. We assessed scar healing at 6 weeks.

RESULTS

920 women completed telephone questionnaires. Wound healing did not differ significantly among the clusters: the healing complication rate was 21% in the control group (n=46) and ranged from 18% to 26% (n=27-50) in clusters two to five (P=0.49). More healing complications were observed in women with a body mass index (BMI) of more than 35 kg/m versus 35 kg/m or less (P=0.016), urgent versus elective CD (P=0.013), preterm premature rupture of the membranes (PPROM) versus intact membranes (P=0.016), and chorioamnionitis at delivery versus no chorioamnionitis (P=0.001). 586 (64%) women underwent physician assessment at staples removal and at 6 weeks post CD.

CONCLUSIONS

Timing of dressing and staples removal has no effect on CD scar healing in low- and high-risk parturients. A BMI of more than 35 kg/m , urgent CD, PPROM, and chorioamnionitis were associated with mal-healing, regardless of cluster. Clinicaltrials.gov: NCT01724255.

摘要

目的

探讨剖宫产术后(CD)敷料和缝线去除的最佳时机。

方法

本前瞻性聚类临床试验纳入了 2013 年 1 月 1 日至 2014 年 10 月 31 日期间在耶路撒冷哈达萨希伯来大学医院接受 CD 的女性。女性被分配到五个不同敷料和缝线去除时间的聚类之一。我们在 6 周时评估了疤痕愈合情况。

结果

920 名女性完成了电话问卷调查。在聚类之间,伤口愈合没有明显差异:对照组(n=46)的愈合并发症发生率为 21%,而聚类 2 至 5 的发生率为 18%至 26%(n=27-50)(P=0.49)。BMI 超过 35kg/m2 的女性比 BMI 为 35kg/m2 或更低的女性(P=0.016)、紧急 CD 比择期 CD(P=0.013)、胎膜早破(PPROM)比胎膜完整(P=0.016)、分娩时绒毛膜羊膜炎比无绒毛膜羊膜炎(P=0.001)的愈合并发症更多。586 名(64%)女性在缝线去除时和 CD 后 6 周时接受了医生评估。

结论

在低危和高危产妇中,敷料和缝线去除的时机对 CD 疤痕愈合没有影响。BMI 超过 35kg/m2、紧急 CD、PPROM 和绒毛膜羊膜炎与愈合不良有关,与聚类无关。Clinicaltrials.gov:NCT01724255。

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