Dyagil I S, Sholoyko V V, Silayev Yu O, Martina Z V, Dmytrenko I V, Tovstogan A O, Fedorenko V G, Shlyakhtychenko T Yu, Minchenko Zh M
State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», 53 Melnykova str., Kyiv, 04050, Ukraine.
Probl Radiac Med Radiobiol. 2018 Dec;23:517-523. doi: 10.33145/2304-8336-2018-23-517-523.
In this paper, a clinical case of combination of chronic myeloid leukemia and T-lymphoblastic lymphoma is present-ed, which is currently a rather rare finding for a clinician. The diagnosis of T-lymphoblastic lymphoma is establishedafter 2 years from the verification of chronic myeloid leukemia. The course of diseases and approaches to treatmentare described.The pathogenetic relationship between myeloid and lymphoid diseases remains unclear and is likely to be the resultof several factors - radiation, chemical and, consequently, genetic disorders.
本文介绍了一例慢性髓性白血病合并T淋巴细胞母细胞淋巴瘤的临床病例,这对临床医生来说目前是相当罕见的发现。T淋巴细胞母细胞淋巴瘤的诊断是在慢性髓性白血病确诊2年后确立的。文中描述了疾病过程及治疗方法。髓系疾病和淋巴系疾病之间的发病机制关系仍不清楚,可能是多种因素导致的结果——辐射、化学因素,进而引发基因紊乱。