Wohlfahrt Johan Caspar, Aass Anne M, Koldsland Odd C
Department of Periodontology, Institute of Clinical Dentistry, University of Oslo, Oslo, Norway.
Int J Dent Hyg. 2019 May;17(2):170-176. doi: 10.1111/idh.12381. Epub 2019 Feb 7.
This aim of this study was to evaluate a chitosan brush for the treatment of peri-implant mucositis.
A total of 11 patients with a combined total of 24 dental implants and who were diagnosed with peri-implant mucositis were included in this 6-month, split mouth, pilot clinical trial. Implants were randomly assigned to either treatment with a chitosan brush using an oscillating dental hand piece or treatment with titanium curettes. Supportive treatment was provided at 3 months. Two calibrated periodontists, blinded to treatment group, performed all examinations, including probing pocket depths (PPD) and bleeding on probing (mBoP). The changes in clinical parameters were compared between groups at 2 weeks, 4 weeks and 6 months. A Mann-Whitney U test with an alpha level of 0.05 was used for the statistical analyses.
Both groups demonstrated significant reductions in mBoP between baseline and 6 months. The test implants treated with the chitosan brush had a better improvement in mBoP at 2 weeks and 4 weeks compared to the implants treated with the titanium curettes. The reduction in PPD was significantly better in the test group at 4 weeks. All implants had stable bone levels, as seen on radiographs between baseline and 6 months.
Reduced signs of inflammation were seen in both groups 6 months after the baseline treatment and 3 months after maintenance. A chitosan brush seems to be a safe and efficient device for debridement of dental implants.
本研究旨在评估一种壳聚糖刷用于治疗种植体周围黏膜炎的效果。
本为期6个月的半口试点临床试验纳入了11例患者，共计24颗牙种植体，均被诊断为种植体周围黏膜炎。种植体被随机分为两组，一组使用振荡牙科手机配合壳聚糖刷进行治疗，另一组使用钛刮治器进行治疗。在3个月时提供支持性治疗。两名经过校准的牙周病医生在不知道治疗组的情况下进行所有检查，包括探诊深度（PPD）和探诊出血（mBoP）。比较两组在2周、4周和6个月时临床参数的变化。采用α水平为0.05的曼-惠特尼U检验进行统计分析。
两组在基线时和6个月时mBoP均有显著降低。与使用钛刮治器治疗的种植体相比，使用壳聚糖刷治疗的试验种植体在2周和4周时mBoP改善更好。在4周时，试验组PPD的降低明显更好。在基线时和6个月时的X线片显示，所有种植体的骨水平稳定。
在基线治疗6个月后和维持治疗3个月后，两组炎症迹象均减轻。壳聚糖刷似乎是一种安全有效的牙种植体清创器械。
