Fan Xiaoli, Zhao Chaoyi, Luo Hong, Zhang Wei
AQSIQ Key Laboratory of Human Factors and Ergonomics, China National Institute of Standardization, Beijing 100191, P.R.China.
AQSIQ Key Laboratory of Human Factors and Ergonomics, China National Institute of Standardization, Beijing 100191,
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2018 Dec 25;35(6):837-844. doi: 10.7507/1001-5515.201801064.
The electroencephalographic characteristics of mental fatigue, which was induced by long-term working memory task of 2-back, were studied by event-related potential (ERP) technology in order to obtain objective evaluation indicators for mental fatigue. Thirty-two healthy male subjects, 22-28 years old, were divided into two groups evenly, one is un-fatigue group and the other is fatigue group. The fatigue group performed a 2-back task for 100 min continuously, while the un-fatigue group just performed a 2-back task at the first and last 10 min respectively, and rested during the middle 80 min. The subjective levels of fatigue, task performance and electroencephalogram were recorded. The impaired thought and attention states, enhanced sleepy and fatigue feeling were found in the fatigue group, meanwhile their reaction time to 2-back task extended, and the accuracy decreased significantly. These results verified the validity of mental fatigue model induced by 2-back task, and then the ERP characteristic parameters were compared and analyzed between fatigue group and un-fatigue group. The results showed that the fatigue group's amplitudes of P300 ( = 2.539, < 0.05) and error-related negativity (ERN) ( = 10.040, < 0.05) decreased significantly along with the increase of fatigue comparing with the un-fatigue group, however, there were no significant change in other parameters (all > 0.05). These results demonstrate that P300 and ERN can be considered as potential evaluation indictors for mental fatigue induced by long-term working memory task, which will provide basis for the future exploring of countermeasure for mental fatigue.
为了获得精神疲劳的客观评估指标，采用事件相关电位（ERP）技术研究了由2-back长期工作记忆任务诱发的精神疲劳的脑电图特征。32名年龄在22至28岁之间的健康男性受试者被平均分为两组，一组为未疲劳组，另一组为疲劳组。疲劳组连续进行100分钟的2-back任务，而未疲劳组仅在开始和最后10分钟分别进行2-back任务，中间80分钟休息。记录了疲劳的主观水平、任务表现和脑电图。发现疲劳组存在思维和注意力状态受损、困倦和疲劳感增强的情况，同时他们对2-back任务的反应时间延长，准确性显著下降。这些结果验证了2-back任务诱发精神疲劳模型的有效性，然后对疲劳组和未疲劳组的ERP特征参数进行了比较和分析。结果表明，与未疲劳组相比，疲劳组的P300波幅（t = 2.539，P < 0.05）和错误相关负波（ERN）（t = 10.040，P < 0.05）随着疲劳程度的增加而显著降低，然而，其他参数没有显著变化（均P > 0.05）。这些结果表明，P300和ERN可被视为长期工作记忆任务诱发精神疲劳的潜在评估指标，这将为未来探索精神疲劳的对策提供依据。
