Liu Min, Zhang Lei, Guo Liang, Lv Jincai, Shi Weiyan, Liu Bailong
Department of Radiation Oncology, The First Hospital, Jilin University, Changchun 130021, China,
Department of Radiology, The First Hospital, Jilin University, Changchun 130021, China.
Onco Targets Ther. 2018 Dec 3;11:8599-8603. doi: 10.2147/OTT.S180949. eCollection 2018.
Intestinal metastasis from breast cancer (BC) is rarely encountered in clinical practice. Nonspecific symptoms and long latency result in misdiagnosis as a primary intestinal tumor. Therefore, increased awareness of bowel metastasis secondary to BC and a thorough understanding of the clinical and molecular features, and intervention of bowel metastasis are fundamental to avoid the delay of correct diagnosis and management. Herein, we documented a BC patient who experienced progressive bellyache and vomiting 16 years after simplified radical mastectomy. Abdominal CT scan revealed localized thickening of the small intestine wall and lumen narrowing, initially diagnosed as a primary intestinal tumor. The subsequent operation resolved the intestinal obstruction and confirmed the diagnosis of intestinal involvement of BC. Radical local treatment followed by systemic intervention contributed to a better outcome. Our case indicates that intestinal metastasis should be included in the diagnostic checklist in patients presented with any intestinal symptom even with a remote history of BC. Our case is of great value in its rarity and calls for the awareness of clinicians for this special entity to guarantee the accurate and prompt diagnosis and treatment, and optimize the patient's prognosis.
乳腺癌(BC)的肠道转移在临床实践中很少见。非特异性症状和较长的潜伏期导致其被误诊为原发性肠道肿瘤。因此,提高对BC继发性肠道转移的认识,深入了解其临床和分子特征,并对肠道转移进行干预,对于避免正确诊断和治疗的延误至关重要。在此,我们记录了一名BC患者,该患者在简化根治性乳房切除术后16年出现进行性腹痛和呕吐。腹部CT扫描显示小肠壁局限性增厚和管腔狭窄,最初被诊断为原发性肠道肿瘤。随后的手术解除了肠梗阻,并确诊为BC肠道受累。根治性局部治疗后进行全身干预取得了更好的效果。我们的病例表明,即使患者有BC的远期病史,出现任何肠道症状时,肠道转移都应列入诊断清单。我们的病例因其罕见性具有重要价值,呼吁临床医生关注这一特殊情况,以确保准确、及时的诊断和治疗,并优化患者的预后。