Najari Fares, Mostafazadeh Babak, Akbari Asadollah, Baradaran Kaya Ideh, Najari Dorsa
Forensic Medicine Department, Shohadaye Tajrish Hospital, Medical Faculty, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Legal Medicine Organization, Tehran, Iran.
Emerg (Tehran). 2018;6(1):e48. Epub 2018 Aug 7.
Pulmonary embolism (PE) is introduced as the third major cause of death after trauma in those who survive more than 24 hours This study aimed to describe the characteristics of mortalities due to trauma related PE in cases referred to the forensic medicine department.
The present cross sectional study was conducted on medical profiles of cadavers that were registered as trauma related mortality in the dissection department of the Forensic Medicine Organization, Tehran, Iran, during 2011 to 2016.
The cause of death for 92 of the 10800 (0.85%) evaluated cadavers was diagnosed as trauma related PE. The mean age of these patients was 58.37 ± 19.39 years (66.3% male). Only 14 (15.2%) hospitalized patients had received anticoagulant agents. The most frequent trauma related PE mortality cases were male (p = 0.003) and aged > 55 years (p = 0.005), with trauma to death time of < 3 weeks (p = 0.004), lower limb injury (p = 0.003), car crash trauma mechanism (p = 0.003), and no anticoagulant prescribed (p = 0.001).
According to the results of the present study, the prevalence of trauma related PE mortality was 0.85%. It seems that, having a clear anticoagulation therapy protocol in trauma centers could be helpful in decreasing the prevalence of traumatic thromboembolism and its' related mortality.
肺栓塞（PE）被认为是创伤后存活超过24小时患者的第三大死亡原因。本研究旨在描述法医部门所接收的创伤相关性肺栓塞死亡病例的特征。
本横断面研究针对2011年至2016年期间在伊朗德黑兰法医组织解剖部门登记为创伤相关死亡的尸体的医学资料进行。
在10800具评估尸体中，有92例（0.85%）的死亡原因被诊断为创伤相关性肺栓塞。这些患者的平均年龄为58.37±19.39岁（男性占66.3%）。只有14名（15.2%）住院患者接受了抗凝剂治疗。创伤相关性肺栓塞死亡病例中最常见的是男性（p = 0.003）、年龄>55岁（p = 0.005）、创伤至死亡时间<3周（p = 0.004）、下肢损伤（p = 0.003）、车祸创伤机制（p = 0.003）以及未开具抗凝剂（p = 0.001）。
根据本研究结果，创伤相关性肺栓塞死亡率为0.85%。在创伤中心制定明确的抗凝治疗方案似乎有助于降低创伤性血栓栓塞及其相关死亡率。
