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孕期酒精和药物使用风险筛查:年轻女性与成年女性相比情况如何?

Screening for At-Risk Alcohol and Drug Use in the Antenatal Period: How Do Young Women Compare with Older Adult Women?

作者信息

Kelpin Sydney S, Rusteikas Scott G, Karjane Nicole W, Svikis Dace S

机构信息

Department of Psychology, Virginia Commonwealth University, Richmond, Virginia.

Department of Obstetrics and Gynecology, Virginia Commonwealth University School of Medicine, Richmond, Virginia.

出版信息

J Pediatr Adolesc Gynecol. 2019 Jun;32(3):325-329. doi: 10.1016/j.jpag.2018.12.003. Epub 2018 Dec 22.

Abstract

STUDY OBJECTIVE

In the present study we compared results of standardized screening tools for problem alcohol and other drug use in younger (ages 18-24 years) and older (ages 25 and older) women attending the same clinic. We separately investigated pregnant and nonpregnant women. DESIGN, SETTING, PARTICIPANTS, INTERVENTIONS, AND MAIN OUTCOME MEASURES: This was a cross-sectional study of women attending an urban, university-affiliated obstetrics and gynecology clinic. Women were recruited while awaiting appointments with their providers. In total, 3317 provided consent and completed a brief anonymous survey with standardized questions about alcohol and other drug problems. Measures included the T-ACE (acronym for Tolerance, Annoyed when others express concern, Cut down on drinking, Eye-opener) for alcohol and CAGE for other drugs (CAGE is a mnemonic for the following items: (1) Have you ever felt you should cut down on your use of other drugs? (2) Have people annoyed you by criticizing your use of other drugs? (3) Have you ever felt bad or guilty about your use of other drugs? and (4) Have you ever used drugs first thing in the morning to steady your nerves, avoid withdrawal, or get rid of a hangover [eye opener]?). Individual item responses and screener summary scores were compared separately for pregnant and nonpregnant younger (ages 18-24 years) and older adult (25 years of age or older) women using χ for categorical and t tests for continuous variables.

RESULTS

For pregnant women, 386/1460 (26%) of older women screened at-risk for problem drinking compared to 250/1203 (21%) of younger women (P = .001). For other drugs, however, 192/1203 (16%) of younger pregnant women screened at risk compared to 186/1461 (13%) of older adult pregnant women (P = .02). For nonpregnant women, screen positive rates for at-risk drug use were nearly 2 times higher among older compared with younger women, with 48/321 (15%) of older women screening at risk compared to 28/332 (8%) of younger women (P < .01).

CONCLUSION

The present findings affirm the need for routine screening for alcohol and drug problems in women of all ages, regardless of pregnancy status.

摘要

研究目的

在本研究中,我们比较了在同一家诊所就诊的年轻女性(18 - 24岁)和年长女性(25岁及以上)中,用于筛查酒精及其他药物使用问题的标准化工具的结果。我们分别对孕妇和非孕妇进行了调查。

设计、地点、参与者、干预措施及主要结局指标:这是一项对在城市中一家大学附属妇产科诊所就诊的女性进行的横断面研究。女性在等待与医生预约时被招募。共有3317名女性提供了同意书,并完成了一份简短的匿名调查问卷,其中包含关于酒精和其他药物问题的标准化问题。测量指标包括用于酒精问题筛查的T - ACE(耐受性、他人表达担忧时感到恼怒、减少饮酒量、清晨眼开剂的首字母缩写)和用于其他药物问题筛查的CAGE(CAGE是以下各项的助记符:(1) 你是否曾觉得自己应该减少其他药物的使用?(2) 别人批评你使用其他药物是否让你恼怒?(3) 你是否曾因使用其他药物而感到难过或内疚?(4) 你是否曾在清晨第一件事就是使用药物来稳定神经、避免戒断反应或消除宿醉 [清晨眼开剂]?)。分别使用卡方检验分析分类变量,使用t检验分析连续变量,对孕妇和非孕妇中年轻(18 - 24岁)及年长成年(25岁及以上)女性的个体项目回答和筛查总结分数进行比较。

结果

对于孕妇,1460名年长女性中有386名(26%)筛查出有饮酒问题风险,而1203名年轻女性中有250名(21%)筛查出有饮酒问题风险(P = 0.001)。然而,对于其他药物,1203名年轻孕妇中有192名(16%)筛查出有风险,而1461名年长成年孕妇中有186名(13%)筛查出有风险(P = 0.02)。对于非孕妇,年长女性中药物使用风险筛查阳性率几乎是年轻女性的2倍,321名年长女性中有48名(15%)筛查出有风险,而332名年轻女性中有28名(8%)筛查出有风险(P < 0.01)。

结论

本研究结果证实,无论怀孕状况如何,所有年龄段女性都需要对酒精和药物问题进行常规筛查。

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