Tsakiridis Ioannis, Dagklis Themistoklis, Zerva Christina, Mamopoulos Apostolos, Athanasiadis Apostolos, Papazisis Georgios
3rd Department of Obstetrics and Gynaecology, Faculty of Medicine, Aristotle University of Thessaloniki, Greece.
3rd Department of Obstetrics and Gynaecology, Faculty of Medicine, Aristotle University of Thessaloniki, Greece; Department of Clinical Pharmacology, Faculty of Medicine, Aristotle University of Thessaloniki, Greece.
Midwifery. 2019 Mar;70:71-75. doi: 10.1016/j.midw.2018.12.008. Epub 2018 Dec 13.
Pregnancies complicated with intrauterine growth restriction (IUGR) may require hospitalization in a high-risk pregnancy unit (HRPU). A complicated pregnancy and hospital admission may negatively affect the pregnant woman's mental health. Several factors have been identified as possible risk factors for depression, which is proven to lead to several adverse perinatal outcomes. The purpose of this study was to screen for depression in women admitted to an HRPU due to IUGR pregnancy and also to identify associated risk factors.
All pregnant women admitted at ≥ 24 gestational weeks with the diagnosis of IUGR were eligible for the study. The Greek version of the Edinburgh Postnatal Depression Scale was used as screening tool on admission. A cut-off score ≥ 13 was used to identify depression, while possible risk factors were also investigated.
Overall, 73 women were eligible for the study and agreed to complete the questionnaire. The mean age of the pregnant women was 31.4 ± 6.7 years and the mean gestational week at admission was 33.6 ± 2.9 weeks. The prevalence of depressive symptoms (score ≥ 13) was 32.9% (24/73). In the multivariable model, depressive symptoms were significantly correlated with lower gestational age (OR: 3.459 95%CI: 1.124-10.648) and smoking during pregnancy (OR: 3.926 95% CI: 1.141-13.507).
About one third of pregnant women hospitalized in the HRPU with IUGR pregnancies showed signs of depression at the time of admission. Early-IUGR and smoking were found to be associated with antenatal depressive symptoms.
妊娠合并宫内生长受限（IUGR）可能需要在高危妊娠病房（HRPU）住院治疗。复杂的妊娠情况和住院可能会对孕妇的心理健康产生负面影响。已确定有几个因素可能是抑郁症的风险因素，而抑郁症已被证明会导致多种不良围产期结局。本研究的目的是筛查因IUGR妊娠而入住HRPU的女性中的抑郁症，并确定相关的风险因素。
所有孕周≥24周且诊断为IUGR的住院孕妇均符合本研究条件。入院时使用希腊版的爱丁堡产后抑郁量表作为筛查工具。采用≥13分的临界值来确定是否患有抑郁症，同时还对可能的风险因素进行了调查。
总体而言，73名女性符合研究条件并同意完成问卷调查。孕妇的平均年龄为31.4±6.7岁，入院时的平均孕周为33.6±2.9周。抑郁症状（得分≥13）的患病率为32.9%（24/73）。在多变量模型中，抑郁症状与较低的孕周（比值比：3.459，95%置信区间：1.124 - 10.648）和孕期吸烟（比值比：3.926，95%置信区间：1.141 - 13.507）显著相关。
在HRPU因IUGR妊娠住院的孕妇中，约三分之一在入院时表现出抑郁迹象。发现早期IUGR和吸烟与产前抑郁症状有关。
