Dagklis Themistoklis, Tsakiridis Ioannis, Chouliara Foteini, Mamopoulos Apostolos, Rousso David, Athanasiadis Apostolos, Papazisis Georgios
a Third Department of Obstetrics and Gynaecology, Faculty of Medicine , Aristotle University of Thessaloniki , Greece.
b Department of Clinical Pharmacology, Faculty of Medicine , Aristotle University of Thessaloniki , Greece.
J Matern Fetal Neonatal Med. 2018 Apr;31(7):919-925. doi: 10.1080/14767058.2017.1301926. Epub 2017 Mar 21.
Estimates for the prevalence of antenatal depression vary widely across different studies and especially concerning high-risk pregnancies. Threatened preterm labor is the most common indication for antenatal obstetric hospitalization. The aim of this study was to screen for depressive symptoms among pregnant women hospitalized in a high-risk pregnancy unit due to threatened preterm labor and also to investigate possible associated risk factors.
A total of 103 pregnant women admitted at >24 and <36 gestational weeks were eligible to participate in the study. The Greek version of the Edinburgh Postnatal Depression Scale (EPDS) was used to detect depressive symptoms on admission. A cutoff score of >13 was considered as indicative of depression. Possible associated risk factors were also investigated.
The prevalence of antenatal depression (score >13) was 24.3% (n = 25). In the multivariate analysis, antenatal depression was significantly correlated with thoughts of abortion (OR: 6.208; 95% CI: 1.141-33.765).
About one quarter of the pregnant women hospitalized in the HRPU due to threatened preterm labor were depressed based on the EPDS. Thoughts of abortion were associated with a sixfold increase in the risk of depression, while no associations were found between antenatal depression and other sociodemographic and obstetric parameters.
不同研究中关于产前抑郁症患病率的估计差异很大，尤其是在高危妊娠方面。先兆早产是产前产科住院最常见的指征。本研究的目的是筛查因先兆早产而入住高危妊娠病房的孕妇中的抑郁症状，并调查可能的相关危险因素。
共有103名孕周在24周以上且小于36周的孕妇符合参与本研究的条件。采用希腊版爱丁堡产后抑郁量表（EPDS）在入院时检测抑郁症状。得分大于13分被视为抑郁的指征。还对可能的相关危险因素进行了调查。
产前抑郁症（得分>13）的患病率为24.3%（n = 25）。在多变量分析中，产前抑郁症与流产想法显著相关（比值比：6.208；95%置信区间：1.141 - 33.765）。
根据EPDS，因先兆早产入住高危妊娠病房的孕妇中约四分之一患有抑郁症。流产想法与抑郁症风险增加六倍相关，而产前抑郁症与其他社会人口统计学和产科参数之间未发现关联。
