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类固醇诱导的肾上腺功能不全促成布里斯班分枝杆菌肺部感染

Mycobacterium brisbanense lung infection facilitated by steroid induced adrenal insufficiency.

作者信息

Gynthersen Rosa, Qvist Tavs, Andersen Åse B, Katzenstein Terese L

机构信息

Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark.

出版信息

APMIS. 2019 Feb;127(2):106-108. doi: 10.1111/apm.12911. Epub 2018 Dec 25.

Abstract

Mycobacterium brisbanense is rapid-growing nontuberculous mycobacteria. It was first described in 2004 as a human pathogen and only one case report has previously been published. We report a case of M. brisbanense infection in a young man with asthma, recurrent lung infections and secondary adrenal insufficiency induced by inhalation steroids and itraconazole use. The mycobacterial infection was successfully treated with a long-term multidrug regimen.

摘要

布里斯班分枝杆菌是快速生长的非结核分枝杆菌。它于2004年首次被描述为一种人类病原体,此前仅发表过一例病例报告。我们报告了一例布里斯班分枝杆菌感染病例,患者为一名患有哮喘、反复肺部感染以及因吸入性类固醇和使用伊曲康唑导致继发性肾上腺功能不全的年轻男性。该分枝杆菌感染通过长期多药联合方案成功治愈。

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