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估计美国男男性行为者、注射毒品者和异性恋者中的 HIV 感染率。

Estimating national rates of HIV infection among MSM, persons who inject drugs, and heterosexuals in the United States.

机构信息

Division of HIV/AIDS Prevention, the U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

出版信息

AIDS. 2019 Mar 15;33(4):701-708. doi: 10.1097/QAD.0000000000002111.

Abstract

BACKGROUND

Calculating national rates of HIV diagnosis, incidence, and prevalence can quantify disease burden, and is important for planning and evaluating programs. We calculated HIV rates among MSM, persons who inject drugs (PWID), and heterosexuals in 2010 and 2015.

METHODS

We used proportion estimates of the US population classified as MSM, PWID, and heterosexuals along with census data to calculate the population sizes which were used as the denominators for calculating HIV rates. The numerators (HIV diagnosis, incidence, and prevalence) were based on data submitted to the National HIV Surveillance System through June 2017.

RESULTS

The estimated HIV diagnosis and incidence rates in 2015 were 574.7 and 583.6 per 100 000 MSM; 34.3 and 32.7 per 100 000 PWID; and 4.1 and 3.8 per 100 000 heterosexuals. The estimated HIV prevalence in 2015 was 12 372.9 per 100 000 MSM; 1937.2 per 100 000 PWID; and 126.7 per 100 000 heterosexuals. The HIV diagnosis rates decreased from 2010 to 2015 in all three transmission categories. Black individuals had the highest HIV diagnosis rates at both time points. The HIV incidence rates decreased among white MSM, MSM aged 13-24 years, PWID overall, and male and female heterosexual individuals; however, it increased among MSM aged 25-34 years.

CONCLUSIONS

The estimated HIV diagnosis and HIV infection rates decreased for several transmission categories, and also race/ethnicity and age subgroups. MSM continue to be disproportionately affected. Disparities remain and have widened for some groups. Efforts are needed to strengthen prevention, care, and supportive services for all persons with HIV infection.

摘要

背景

计算全国范围内 HIV 的诊断率、发病率和感染率可以量化疾病负担,对于规划和评估项目非常重要。我们计算了 2010 年和 2015 年男男性行为者(MSM)、注射吸毒者(PWID)和异性恋者中的 HIV 感染率。

方法

我们使用美国人口中归类为 MSM、PWID 和异性恋者的比例估计值以及人口普查数据来计算人群规模,这些规模被用作计算 HIV 感染率的分母。分子(HIV 诊断、发病率和感染率)基于截至 2017 年 6 月向国家艾滋病毒监测系统提交的数据。

结果

2015 年估计的 HIV 诊断率和发病率分别为每 100000 名 MSM 中 574.7 和 583.6 例;每 100000 名 PWID 中 34.3 和 32.7 例;每 100000 名异性恋者中 4.1 和 3.8 例。2015 年估计的 HIV 感染率为每 100000 名 MSM 中 12372.9 例;每 100000 名 PWID 中 1937.2 例;每 100000 名异性恋者中 126.7 例。从 2010 年到 2015 年,所有三个传播类别中的 HIV 诊断率均下降。在这两个时间点,黑人的 HIV 诊断率均最高。白人 MSM、13-24 岁 MSM、整体 PWID、男性和女性异性恋者的 HIV 发病率均下降;然而,25-34 岁 MSM 的 HIV 发病率却有所上升。

结论

几个传播类别、种族/民族和年龄亚组的 HIV 诊断率和 HIV 感染率有所下降。MSM 仍然受到不成比例的影响。一些群体的差异仍然存在并有所扩大。需要努力加强所有 HIV 感染者的预防、护理和支持性服务。

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