Krajewska-Wędzina Monika, Augustynowicz-Kopeć Ewa, Weiner Marcin, Szulowski Krzysztof
Department of Microbiology, National Veterinary Research Institute, Pulawy, Poland.
Department of Microbiology, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland.
Ann Agric Environ Med. 2018 Dec 19;25(4):593-595. doi: 10.26444/aaem/75685. Epub 2017 Jul 5.
Bovine tuberculosis (bTB) is an infectious disease that occurs in many species of both domestic and free-ranging animals, as well as animals kept in zoos. According to the Polish regulations, cattle tuberculosis are slaughtered and microbiological examinations are performed, the rest of animal species can be treated and laboratory diagnostics are not obligatory.
The presented case concerns two male giraffes which were purchased by the zoo and united with a third male. After a year, the oldest male died. Post mortem examinations confirmed generalized tuberculosis. After a further six months, the second male was euthanized after suffering great pain. The material for the study of drug resistance was a swab from the nose, obtained ante mortem from the third male. Attempted treatments did not produce the expected results. Genotyping allowed the exclusion of a common source of transmission.
The final effect of the anti-tuberculosis therapy in the male giraffe raises the question whether the research team should have undertaken the treatment of the animal with active tuberculosis.
牛结核病(bTB)是一种发生于许多家养和自由放养动物物种以及动物园饲养动物的传染病。根据波兰法规,感染结核病的牛会被屠宰并进行微生物学检查,其他动物物种可以接受治疗,实验室诊断并非强制要求。
本病例涉及两只雄性长颈鹿,它们被动物园购买并与第三只雄性长颈鹿合群。一年后,最年长的雄性长颈鹿死亡。尸检证实患有全身性结核病。又过了六个月,第二只雄性长颈鹿在遭受巨大痛苦后被安乐死。用于耐药性研究的材料是在第三只雄性长颈鹿生前采集的鼻拭子。尝试的治疗未产生预期效果。基因分型排除了共同传播源。
雄性长颈鹿抗结核治疗的最终结果引发了一个问题,即研究团队是否本应着手治疗患有活动性结核病的动物。