评估成人和儿童脊柱畸形患者中患者报告结果测量信息系统（PROMIS）与脊柱侧凸研究学会（SRS）问卷的相关性及性能。
Evaluating the Correlation and Performance of PROMIS to SRS Questionnaires in Adult and Pediatric Spinal Deformity Patients.
作者信息
Bernstein David N, Papuga M Owen, Sanders James O, Rubery Paul T, Menga Emmanuel N, Mesfin Addisu
机构信息
Department of Orthopaedic Surgery, University of Rochester, 601 Elmwood Ave, Box 665, Rochester, NY 14642, USA.
Research Department, New York Chiropractice College, 2360 State Route 89, Seneca Falls, NY 13148, USA.
出版信息
Spine Deform. 2019 Jan;7(1):118-124. doi: 10.1016/j.jspd.2018.05.010.
STUDY DESIGN
Retrospective cross-sectional cohort analysis.
OBJECTIVES
- To assess the correlation of Patient-Reported Outcomes Management Information System (PROMIS) domains with SRS-22r/SRS-30 domains in all scoliosis patients; 2) to assess the correlation of PROMIS domains with SRS-30 domains in adult scoliosis patients; 3) to assess the correlation of PROMIS domains with SRS-22r/SRS-30 domains in pediatric scoliosis patients; and 4) to assess ceiling and floor effects of PROMIS and SRS-22r/SRS-30 domains.
SUMMARY OF BACKGROUND DATA
Studies evaluating correlations between PROMIS and a number of legacy PRO tools have been conducted. To our knowledge, no literature exists examining the correlation of PROMIS and SRS questionnaires in adult and pediatric spinal deformity patients.
METHODS
Outpatient visits from July 2015 to December 2017 with concurrent PROMIS and SRS questionnaires were analyzed. Pediatric patients completed the SRS-22r, whereas adults completed the SRS-30. PROMIS measured Physical Function/Mobility, Pain Interference, and Depression domains. Spearman correlation coefficients (ρ) were calculated. Ceiling and floor effects were calculated and compared.
RESULTS
227 (164 adult; 64 pediatric) patient visits representing 173 patients were included. Moderate to strong correlation existed between PROMIS Physical Function/Mobility and SRS Function/Activity (F/A) domains (ρ, range 0.59-0.84; p < .001). PROMIS Pain Interference and SRS Pain domains showed strong-moderate to strong correlation (ρ, range -0.68 to -0.83; p < .001). PROMIS Depression and SRS Mental Health (MH) domains demonstrated strong-moderate to strong correlation (ρ, range -0.67 to -0.80; p < .001). Ceiling and floor effects were all less in PROMIS domains (range, 0.44% to 0.88%) compared with SRS domains (range, 0.88% to 17.62%).
CONCLUSIONS
PROMIS Physical Function/Mobility, Pain Interference, and Depression domains correlate well with SRS F/A, Pain, and MH. SRS SI/A and Satisfaction are not as well captured. PROMIS showed better ceiling and floor effects than SRS.
LEVEL OF EVIDENCE
Level III.
研究设计
回顾性横断面队列分析。
目的
1）评估所有脊柱侧弯患者中患者报告结局管理信息系统（PROMIS）领域与SRS - 22r/SRS - 30领域的相关性；2）评估成年脊柱侧弯患者中PROMIS领域与SRS - 30领域的相关性；3）评估儿童脊柱侧弯患者中PROMIS领域与SRS - 22r/SRS - 30领域的相关性；4）评估PROMIS和SRS - 22r/SRS - 30领域的天花板效应和地板效应。
背景数据总结
已开展了评估PROMIS与许多传统患者报告结局工具之间相关性的研究。据我们所知，尚无文献研究PROMIS与成人及儿童脊柱畸形患者的SRS问卷之间的相关性。
方法
分析2015年7月至2017年12月期间同时进行PROMIS和SRS问卷调查的门诊就诊情况。儿童患者完成SRS - 22r，而成人患者完成SRS - 30。PROMIS测量身体功能/活动能力、疼痛干扰和抑郁领域。计算Spearman相关系数（ρ）。计算并比较天花板效应和地板效应。
结果
纳入了代表173例患者的227次（164例成人；64例儿童）患者就诊情况。PROMIS身体功能/活动能力与SRS功能/活动（F/A）领域之间存在中度至高度相关性（ρ，范围0.59 - 0.84；p <.001）。PROMIS疼痛干扰与SRS疼痛领域显示出中度至高度相关性（ρ，范围 - 0.68至 - 0.83；p <.001）。PROMIS抑郁与SRS心理健康（MH）领域表现出中度至高度相关性（ρ，范围 - 0.67至 - 0.80；p <.001）。与SRS领域（范围0.88%至17.62%）相比，PROMIS领域的天花板效应和地板效应均较小（范围0.44%至0.88%）。
结论
PROMIS身体功能/活动能力、疼痛干扰和抑郁领域与SRS F/A、疼痛和MH相关性良好。SRS的自我形象/外观（SI/A）和满意度未得到很好体现。PROMIS的天花板效应和地板效应比SRS更好。
证据级别
三级。
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