Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
Sealy Center on Aging, University of Texas Medical Branch, Galveston, TX, USA.
Aging Ment Health. 2020 Mar;24(3):413-422. doi: 10.1080/13607863.2018.1544214. Epub 2018 Dec 27.
: To evaluate associations between depression and individual cognitive domains and how changes in depressive symptoms relate to cognition three years later in the context of Mexico, a developing country experiencing rapid aging.: Data comes from the 2012 and 2015 waves of the Mexican Health and Aging Study ( = 12,898, age 50+). Depression is ascertained using a modified Center for Epidemiologic Studies - Depression Scale. Cognition is assessed using verbal learning, verbal memory, visual scanning, verbal fluency, visuospatial ability, visual memory, and orientation tasks. Depressive symptoms and cognitive functioning were both measured in 2012 and 2015. Scores across cognitive domains are modeled using ordinary least squares regression, adjusting for demographic, health, and economic covariates.: When depression and cognition were measured concurrently in 2015, depression exhibited associations with all cognitive domains. When considering a respondent's history of depression, individuals who had elevated depressive symptoms in 2012 and recovered by 2015 continued to exhibit poorer cognitive function in 2015 in verbal learning, verbal memory, visual scanning, and verbal fluency tasks compared to individuals who were neither depressed in 2012 nor 2015.: Depression was associated with cognition across cognitive domains among older Mexican adults. Despite improvements in depressive symptomatology, formerly depressed respondents continued to perform worse than their counterparts without a history of depression on several cognitive tasks. In addition to current mental health status, researchers should consider an individual's history of depression when assessing the cognitive functioning of older adults.
为了评估在墨西哥这个老龄化迅速发展的发展中国家的背景下,抑郁与个体认知领域之间的关联,以及抑郁症状的变化如何与三年后的认知相关,我们收集了墨西哥健康与老龄化研究(2012 年和 2015 年的调查数据)的数据。 = 12898 名年龄在 50 岁及以上的参与者)。抑郁采用改良的流行病学研究中心抑郁量表来确定。认知使用词语学习、词语记忆、视觉扫描、词语流畅性、视觉空间能力、视觉记忆和定向任务来评估。抑郁症状和认知功能在 2012 年和 2015 年都进行了测量。使用普通最小二乘回归对认知领域的分数进行建模,调整了人口统计学、健康和经济因素。当抑郁和认知在 2015 年同时测量时,抑郁与所有认知领域都有相关性。当考虑一个人的抑郁史时,那些在 2012 年有较高抑郁症状并在 2015 年恢复的人,与那些在 2012 年和 2015 年都没有抑郁的人相比,在词语学习、词语记忆、视觉扫描和词语流畅性任务中的认知功能仍然较差。在墨西哥老年成年人中,抑郁与认知领域的认知相关。尽管抑郁症状有所改善,但以前抑郁的受访者在几个认知任务上的表现仍不如没有抑郁史的受访者。除了当前的心理健康状况外,研究人员在评估老年人的认知功能时,还应考虑个体的抑郁史。