Hodžić Enisa, Durek Adnan, Begić Edin, Šabanović Bajramović Nirvana
Clinic for Heart, Blood Vessel and Rheumatic Diseases, Clinical Center, University of Sarajevo, Sarajevo, Department for Internal Medicine, School of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Department of Psychiatry, Cantonal Hospital Travnik, Travnik, Bosnia and Herzegovina.
Med Glas (Zenica). 2019 Feb 1;16(1):35-39. doi: 10.17392/981-19.
Aim To investigate etiological link between acute myocardial infarction (AMI) and the accompanying impotence/erectile dysfunction (ED). Methods Study included 99 male patients (48 who had AMI - patient group, and 51 healthy examinees without previous cardiovascular disease - control group). All patients completed a standardized questionnaire, the International Index of Erectile Function (IIEF-5). Results Older patients had significantly lower IIEF-5 score (negative correlation) (p<0.05), but higher ED degree (significant positive correlation) (rho=0.522; p=0.0001). In the patient group, 37 (77.1%) patients had ED, while in the control group it was found in 26 (51%) examinees (p<0.05). A clear correlation was found between incidence of ED and diabetes, dyslipidaemia, hypertension and positive family history (they were more common in patients with ED, with no statistically significant difference). There was no statistically significant difference between patients with ED and patients without ED according to the beta-blocker usage (p=0.824): ED was reported in 11 (68%) patients in the group who used carvedilol, 14 (82.3%) in the group who used metoprolol, and nine (81.8%) who used nebivolol. Conclusion Myocardial infarction as well as age are directly related to the occurrence of ED. Cardiovascular risk factors are in direct correlation for the occurrence of erectile dysfunction after myocardial infarction.
目的 探讨急性心肌梗死(AMI)与伴发的阳痿/勃起功能障碍(ED)之间的病因学联系。方法 研究纳入99例男性患者(48例患有AMI的患者组,以及51例无既往心血管疾病的健康体检者——对照组)。所有患者均完成了一份标准化问卷,即国际勃起功能指数(IIEF-5)。结果 年龄较大的患者IIEF-5评分显著较低(负相关)(p<0.05),但ED程度较高(显著正相关)(rho=0.522;p=0.0001)。在患者组中,37例(77.1%)患者患有ED,而在对照组中,26例(51%)体检者存在ED(p<0.05)。发现ED的发生率与糖尿病、血脂异常、高血压和阳性家族史之间存在明显相关性(它们在ED患者中更为常见,无统计学显著差异)。根据β受体阻滞剂的使用情况,有ED的患者和无ED的患者之间无统计学显著差异(p=0.824):使用卡维地洛的组中有11例(68%)患者报告有ED,使用美托洛尔的组中有14例(82.3%),使用奈必洛尔的组中有9例(81.8%)。结论 心肌梗死以及年龄与ED的发生直接相关。心血管危险因素与心肌梗死后勃起功能障碍的发生直接相关。