Haykal Tarek, Rahman Al Bizri Abdul, Dawood Thair, Osterholzer Danielle
Hurley Medical Center, Department of Internal Medicine, Flint, MI, USA.
Michigan State University, College of Human Medicine, East Lansing, MI, USA.
IDCases. 2018 Dec 21;15:e00476. doi: 10.1016/j.idcr.2018.e00476. eCollection 2019.
Para-aortic root abscess is a destructive vascular condition that can result in significant morbidity and mortality. We describe a rare case of para-aortic root abscess due to Typhimurium that was successfully managed medically.
A 72-year-old diabetic man with a prosthetic aortic graft presented with fever and expressive aphasia with left sided weakness. Magnetic resonance imaging (MRI) of the brain showed multiple embolic cerebral vascular accidents. Computed tomography angiography (CTA) of the chest showed a 5.7 × 2.7 cm (cm) para-aortic root abscess. Blood cultures grew Typhimurium. The patient was started on ceftriaxone initially, and then ciprofloxacin was added on day 5. Given an unacceptably high risk of mortality expected with surgery, the patient was managed medically.After five months of both ceftriaxone and ciprofloxacin, ceftriaxone was stopped. Twelve months later, the patient is doing well on ciprofloxacin alone with a plan for lifelong suppression.
Cases of para-aortic root abscess due to Typhimurium have not been reported in the literature. There are no guidelines to dictate the antibiotic choice or management of para-aortic root abscess due to Typhimurium.
This report adds to the body of literature regarding the treatment of this infection including successful non-surgical management.
主动脉根部旁脓肿是一种破坏性血管疾病,可导致严重的发病率和死亡率。我们描述了一例罕见的由鼠伤寒沙门氏菌引起的主动脉根部旁脓肿病例,该病例通过药物治疗成功治愈。
一名72岁患有人工主动脉移植物的糖尿病男性患者,出现发热、表达性失语伴左侧肢体无力。脑部磁共振成像(MRI)显示多发性栓塞性脑血管意外。胸部计算机断层血管造影(CTA)显示一个5.7×2.7厘米的主动脉根部旁脓肿。血培养检出鼠伤寒沙门氏菌。患者最初开始使用头孢曲松,然后在第5天加用环丙沙星。鉴于手术预期的死亡率高得不可接受,该患者接受了药物治疗。在使用头孢曲松和环丙沙星五个月后,停用了头孢曲松。十二个月后,患者仅使用环丙沙星情况良好,并计划进行终身抑制治疗。
文献中尚未报道过由鼠伤寒沙门氏菌引起的主动脉根部旁脓肿病例。对于由鼠伤寒沙门氏菌引起的主动脉根部旁脓肿,尚无指导抗生素选择或治疗的指南。
本报告增加了有关这种感染治疗的文献资料,包括成功的非手术治疗。