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主动脉脓肿及瘘管的外科治疗。

Surgical treatment of aortic abscess and fistula.

作者信息

Bozbuga Nilgun, Erentug Vedat, Erdogan Hasan Basri, Kirali Kaan, Ardal Hasan, Tas Serpil, Akinci Esat, Yakut Cevat

机构信息

Department of Cardiovascular Surgery, Kosuyolu Heart and Research Hospital, Kosuyolu, 81020 Istanbul, Turkey.

出版信息

Tex Heart Inst J. 2004;31(4):382-6.

Abstract

The formation of annular abscess and fistulous communication, the most devastating complication of destructive aortic valve endocarditis, requires extensive surgical débridement. Five men experienced destructive native aortic valve endocarditis in association with congestive heart failure (New York Heart Association functional class IV) and hemodynamic deterioration that developed from severe aortic regurgitation. To eradicate the aortic valve endocarditis, we performed (from July 1998 through November 2002) aortic annular skeletonization by dissecting all infectious and necrotic tissue within the abscess cavity and the fistula between the ventriculoarterial junction and the sinotubular junction. The completely resected annular area was covered with a glutaraldehyde-treated autologous pericardial patch that was sutured firmly to fibrous tissue, for a secure proximal anastomosis. Reconstruction of the aortic root was followed by implantation of a Freestyle stentless bioprosthesis, using the aortic root replacement technique. There were no deaths after surgery, nor is there record of a permanent complication due to a loss of conduction tissue. All 5 patients were in New York Heart Association functional class I or II during follow-up (range, 8-56 months). Echocardiography showed no signs of valve dysfunction, recurrent endocarditis, or fistulation. Annular skeletonization and reconstruction of the aortic annulus with glutaraldehyde-treated autologous pericardium permits radical removal of infected tissue and effective treatment of aortic annular abscess, with less risk of valve dehiscence from the fragile aortic annulus.

摘要

环形脓肿和瘘管形成是破坏性主动脉瓣心内膜炎最严重的并发症,需要进行广泛的手术清创。五名男性患有破坏性原发性主动脉瓣心内膜炎,伴有充血性心力衰竭(纽约心脏协会心功能IV级)以及因严重主动脉反流导致的血流动力学恶化。为根除主动脉瓣心内膜炎,我们(从1998年7月至2002年11月)通过解剖脓肿腔内以及心室动脉交界处与窦管交界处之间瘘管内的所有感染和坏死组织,进行了主动脉瓣环骨骼化。完全切除的瓣环区域用经戊二醛处理的自体心包补片覆盖,该补片牢固缝合至纤维组织,以实现安全的近端吻合。在主动脉根部重建后,采用主动脉根部置换技术植入Freestyle无支架生物假体。术后无死亡病例,也没有因传导组织丧失导致永久性并发症的记录。所有5例患者在随访期间(8 - 56个月)均处于纽约心脏协会心功能I级或II级。超声心动图显示无瓣膜功能障碍、复发性心内膜炎或瘘管形成的迹象。用经戊二醛处理的自体心包进行瓣环骨骼化和主动脉瓣环重建,能够彻底清除感染组织,有效治疗主动脉瓣环脓肿,且瓣膜从脆弱的主动脉瓣环处裂开的风险较低。

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